Academic Journal
Development of atrioventricular and intraventricular conduction disturbances in patients undergoing transcatheter aortic valve replacement with new generation self-expanding valves: A real world multicenter analysis.
| العنوان: | Development of atrioventricular and intraventricular conduction disturbances in patients undergoing transcatheter aortic valve replacement with new generation self-expanding valves: A real world multicenter analysis. |
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| المؤلفون: | Castro-Mejía, Alex F, Amat-Santos, Ignacio, Ortega-Armas, Maria E, Baz, Jose A, Moreno, Raúl, Diaz, Jose F, Travieso, Alejandro, Jimenez-Quevedo, Pilar, Santos-Martínez, Sandra, McInerney, Angela, Galeote, Guillermo, Díaz, Victor Alfonso Jimenez, Garrido, Jessica Roa, Tirado-Conte, Gabriela, Barrero, Alejandro, Marroquin, Luis, Nuñez-Gil, Ivan, Gonzalo, Nieves, Fernandez-Ortiz, Antonio, Escaned, Javier, Nombela-Franco, Luis |
| سنة النشر: | 2022 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | Electrocardiographic disturbances, Pacemaker, Self-expanding aortic valves, Transcatheter aortic valve replacement, Aortic Valve, Aortic Valve Stenosis, Cardiac Conduction System Disease, Heart Valve Prosthesis, Humans, Prosthesis Design, Risk Factors, Treatment Outcome |
| الوصف: | High degree cardiac conduction disturbances (HDCD) remain a major complication after transcatheter aortic valve replacement (TAVR), especially with self-expandable valves (SEV). Our aim was to investigate peri-procedural and in-hospital modification of atrioventricular and intracardiac conduction associated to new generation SEV implantation, and the development of new HDCD resulting in permanent pacemaker implantation (PPM) in patients undergoing TAVR. Three-hundred forty-four consecutive patients with severe aortic stenosis who underwent TAVR with a new generation SEV [Evolut-R/Pro (n = 130), Acurate-neo (n = 79), Portico (n = 75) and Allegra (n = 60)] were included. An analysis of baseline, post-TAVR and pre-discharge ECG and procedural aspects were centrally performed. A significant increase in baseline PR interval (169.6 ± 28.2 ms) and QRS complex width (101.7 ± 25.9 ms) was noted immediately post-TAVR (188.04 ± 34.49; 129.55 ± 30.02 ms), with a partial in-hospital reversal (179.4 ± 30.1; 123.06 ± 30.94 ms), resulting in a net increase at hospital discharge of 12.6 ± 38.8 ms and 21.4 ± 31.6 ms (p New generation self-expanding aortic valves were associated with a significant increase in PR and QRS interval at hospital discharge leading to a very high rate of HDCD. While valve recapture and implantation depth were independent predictors for the occurrence of HDCD, use of Accurate-Neo valve was a protective factor. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1874-1754 |
| Relation: | http://hdl.handle.net/10668/22263; https://doi.org/10.1016/j.ijcard.2022.05.014 |
| DOI: | 10.1016/j.ijcard.2022.05.014 |
| الاتاحة: | http://hdl.handle.net/10668/22263 https://doi.org/10.1016/j.ijcard.2022.05.014 |
| Rights: | Attribution-NonCommercial 4.0 International ; http://creativecommons.org/licenses/by-nc/4.0/ ; open access |
| رقم الانضمام: | edsbas.ED114E3B |
| قاعدة البيانات: | BASE |
| تدمد: | 18741754 |
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| DOI: | 10.1016/j.ijcard.2022.05.014 |