Academic Journal
One threat, different answers:the impact of COVID-19 pandemic on cornea donation and donor selection across Europe
| العنوان: | One threat, different answers:the impact of COVID-19 pandemic on cornea donation and donor selection across Europe |
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| المؤلفون: | Thuret, Gilles, Courrier, Emilie, Poinard, Sylvain, Gain, Philippe, Baud'Huin, Marc, Martinache, Isabelle, Cursiefen, Claus, Maier, Philip, Hjortdal, Jesper, Sanchez Ibanez, Jacinto, Ponzin, Diego, Ferrari, Stefano, Jones, Gary, Griffoni, Carlo, Rooney, Paul, Bennett, Kyle, Armitage, W John, Figueiredo, Francisco, Nuijts, Rudy, Dickman, Mor |
| المصدر: | Thuret , G , Courrier , E , Poinard , S , Gain , P , Baud'Huin , M , Martinache , I , Cursiefen , C , Maier , P , Hjortdal , J , Sanchez Ibanez , J , Ponzin , D , Ferrari , S , Jones , G , Griffoni , C , Rooney , P , Bennett , K , Armitage , W J , Figueiredo , F , Nuijts , R & Dickman , M 2022 , ' One threat, different answers : the impact of COVID-19 pandemic on cornea donation and donor .... |
| سنة النشر: | 2022 |
| المجموعة: | Maastricht University Research Publications |
| مصطلحات موضوعية: | epidemiology, eye (tissue) banking, infection, public health, VIRUS TRANSMISSION |
| الوصف: | OBJECTIVES: To assess to which extent the COVID-19 pandemic affected corneal transplantation by virtue of donor selection algorithms in different European countries. DESIGN: Survey. SETTING: 110 eye banks in 26 European countries. PARTICIPANTS: 64 eye banks covering 95% of European corneal transplantation activity. INTERVENTIONS: A questionnaire listing the number of corneas procured and distributed from February to May 2018-2020 was circulated to eye banks. MAIN OUTCOME MEASURES: The primary outcome was the number of corneal procurements. Additional outcomes were national algorithms for donor selection, classified according to their stringency (donors with COVID-19 history, suspected for COVID-19, asymptomatic, PCR testing) and the pandemic severity in each country. We calculated Spearman's correlation coefficient to determine, two by two, the relationship between the 3-month decline in eye banking activity (procurement), the stringency of donor selection algorithm and the grading of pandemic severity (cases and deaths). A partial correlation was run to determine the relationship between decline and stringency while controlling for pandemic severity. RESULTS: Procurements decreased by 38%, 68% and 41%, respectively, in March, April and May 2020 compared with the mean of the previous 2 years, while grafts decreased, respectively, by 28%, 68% and 56% corresponding to 3866 untreated patients in 3 months. Significant disparities between countries and the decrease in activity correlated with stringency in donor selection independent of pandemic severity. CONCLUSIONS: Our data demonstrate significant differences between countries regarding donor screening algorithms based on precautionary principles and, consequently, a decrease in the donor pool, already constrained by a long list of contraindications. Fundamental studies are needed to determine the risk of SARS-CoV-2 transmission by corneal transplantation and guide evidence-based recommendations for donor selection to justify their substantial medical and economic ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1136/bjophthalmol-2020-317938 |
| الاتاحة: | https://cris.maastrichtuniversity.nl/en/publications/768abb68-bb2d-4365-bc7c-9d17378ce4e1 https://doi.org/10.1136/bjophthalmol-2020-317938 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.ECCC43ED |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/bjophthalmol-2020-317938 |
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