Academic Journal
Melanin Production Inhibitors from the West African Cassipourea congoensis
| العنوان: | Melanin Production Inhibitors from the West African Cassipourea congoensis |
|---|---|
| المؤلفون: | Takou, Dieudonné M., Waffo, Alain F. Kamdem, Langat, Moses K., Wansi, Jean D., Mulcahy-Ryan, Lauren E., Schwikkard, Sianne L., Opara, Elizabeth I., Mas-Claret, Eduard, Mulholland, Dulcie |
| بيانات النشر: | Thieme Open |
| سنة النشر: | 2019 |
| المجموعة: | University of Surrey, Guildford: Surrey Scholarship Online. |
| الوصف: | Cassipourea congoensis (syn. Cassipourea malosana) is used in African countries as a skin-lightening agent. Two previously unreported cycloartane triterpenoids, 26-hydroxy-3-keto-24-methy lenecycloartan-30-oic acid 1 and 24-methylene-cycloartan-3β,26,30-triol 2 along with the known mahuannin B 3, 7-methoxymahuannin B 4, 7-methoxygeranin A 5, methyl-3-(4-hydroxy-3-methoxyphenyl)-2E-propenoate, glycerol-1-alkanoate, (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal 6, (-)-syringaresinol 7, and stigmast-5-en-3-O-β-D-glucoside, were isolated from the roots of C. congoensis. The crude extract and compounds 1 and 5 were found to inhibit the production of melanin at 10 μM with low cytotoxicity validating the ethno-medicinal use of this plant |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | http://epubs.surrey.ac.uk/858503/; http://dx.doi.org/10.1055/a-1006-2880; http://epubs.surrey.ac.uk/858503/1/Cassiporea%20congoensis%5B293396%5D.pdf; Takou, Dieudonné M., Waffo, Alain F. Kamdem, Langat, Moses K., Wansi, Jean D., Mulcahy-Ryan, Lauren E., Schwikkard, Sianne L., Opara, Elizabeth I., Mas-Claret, Eduard and Mulholland, Dulcie (2019) Melanin Production Inhibitors from the West African Cassipourea congoensis Planta Medica International Open, 6 (02). e50-e56. |
| DOI: | 10.1055/a-1006-2880 |
| الاتاحة: | http://epubs.surrey.ac.uk/858503/1/Cassiporea%20congoensis%5B293396%5D.pdf https://doi.org/10.1055/a-1006-2880 |
| Rights: | cc_by |
| رقم الانضمام: | edsbas.EC9B9A84 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1055/a-1006-2880 |
|---|