Academic Journal
Portuguese Pancreatic Club Perspectives on Endoscopic Ultrasound-Guided and Surgical Treatment of Pancreatic Neuroendocrine Tumors
| العنوان: | Portuguese Pancreatic Club Perspectives on Endoscopic Ultrasound-Guided and Surgical Treatment of Pancreatic Neuroendocrine Tumors |
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| المؤلفون: | Tiago Ribeiro, Sara Castanheira-Rodrigues, Pedro Bastos, Humberto Cristino, Alexandra Fernandes, Eduardo Rodrigues-Pinto, Miguel Bispo, Ricardo Rio-Tinto, Filipe Vilas-Boas |
| المصدر: | GE: Portuguese Journal of Gastroenterology, Pp 1-11 (2023) |
| بيانات النشر: | Karger Publishers |
| سنة النشر: | 2023 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | ultrassonografia endoscópica, ablação tumoral, duodenopancreatectomia cefálica, radiofrequência, pancreatic neuroendocrine tumors, endoscopic ultrasound, tumor ablation, radiofrequency, surgery, pancreatoduodenectomy, tumores neuroendócrinos do pâncreas, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Pancreatic neuroendocrine tumors (panNETs) are a group of neoplasms with heterogenous biological and clinical phenotypes. Although historically regarded as rare, the incidence of these tumors has been increasing, mostly owing to improvements in the detection of small, asymptomatic tumors with imaging. The heterogeneity of these lesions creates significant challenges regarding diagnosis, staging, and treatment. Endoscopic ultrasound (EUS) has improved the characterization of pancreatic lesions. Furthermore, EUS nowadays has evolved from a purely diagnostic modality to allow the performance of minimally invasive locoregional therapy for pancreatic focal lesions. The choice of treatment as well as the treatment goals depend on several factors, including tumor secretory status, grading, staging, and patient performance status. Surgery has been the mainstay for the management of these patients, particularly for localized, low-grade, large panNETs >2 cm. Over the last decade, a significant body of evidence has been accumulated evaluating the role of EUS for the ablative therapy of panNETs, namely by the use of chemoablative agents and radiofrequency. Although endoscopic techniques are not routinely recommended by international guidelines, they may be considered for the treatment of smaller lesions in patients who are unwilling or unfit for pancreatic surgery. In this review, we summarize the existing evidence on the interventional techniques for the treatment of patients with panNETs, focusing on the EUS-guided and surgical approaches. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2387-1954 |
| Relation: | https://beta.karger.com/Article/FullText/534032; https://doaj.org/toc/2387-1954; https://doaj.org/article/5419c8ccb08642c2837154de6fd93a8c |
| DOI: | 10.1159/000534032 |
| الاتاحة: | https://doi.org/10.1159/000534032 https://doaj.org/article/5419c8ccb08642c2837154de6fd93a8c |
| رقم الانضمام: | edsbas.EC6EB705 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23871954 |
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| DOI: | 10.1159/000534032 |