Academic Journal

DOI:10.1102/1473-1827.2006.0001 Article Sequential determination of individual renal function in atherosclerotic renal artery stenosis

التفاصيل البيبلوغرافية
العنوان: DOI:10.1102/1473-1827.2006.0001 Article Sequential determination of individual renal function in atherosclerotic renal artery stenosis
المؤلفون: Daniela Ricciardi, Christopher Farmer, Gary Cook, John Reidy, John Scoble
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: http://www.journalrenovasculardisease.com/jrdarticles/jrvd060001.pdf.
سنة النشر: 2006
المجموعة: CiteSeerX
الوصف: Background: Atherosclerotic renovascular disease has been increasingly recognised as a common cause of end-stage renal failure in elderly people. The optimum management of this condition is unclear. The aim of this study was the prospective evaluation of the long-term renal outcome in kidneys with atherosclerotic nephropathy. Methods: We have performed sequential individual GFR (glomerular filtration rate) measurements in 115 kidneys where it or its contralateral kidney had angiographically proven atherosclerotic renal artery stenosis over a mean period of 19.37 ± 15.1 months (range 2–66 months). The individual renal function was measured by a synchronous combination of 51chromium ethylene-diamine-tetra-acetic acid GFR (51CrEDTA GFR) and technetium dimercaptosuccinic acid (99mTc DMSA) scintigraphy, the so-called single kidney (SK) GFR test. According to the angiography findings, individual kidneys were divided into four groups: normal, stenosis, occlusion and those treated with balloon angioplasty with or without stent employment. Results: We have calculated the annualised rate of SKGFR change in the four groups of kidney (2.89 ± 8.93 ml/min/year in the normal group, −0.19 ± 4.99 ml/min/year in the stenosis group, 0.66 ± 3.21 ml/min/year in the occlusion group and−1.81±14 ml/min/year in the group of kidneys undergoing percutaneous revascularisation) and no statistically significant difference was found (p> 0.05). For paired kidneys with at least one undergoing
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اللغة: English
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.567.9508; http://www.journalrenovasculardisease.com/jrdarticles/jrvd060001.pdf
الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.567.9508
http://www.journalrenovasculardisease.com/jrdarticles/jrvd060001.pdf
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رقم الانضمام: edsbas.EC69E653
قاعدة البيانات: BASE