Academic Journal
Predicting device failure after percutaneous repair of functional mitral regurgitation in advanced heart failure: Implications for patient selection
| العنوان: | Predicting device failure after percutaneous repair of functional mitral regurgitation in advanced heart failure: Implications for patient selection |
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| المؤلفون: | Stolfo, Davide, De Luca, Antonio, Morea, Gaetano, Merlo, Marco, Vitrella, Giancarlo, Caiffa, Thomas, Barbati, Giulia, Rakar, Serena, Korcova, Renata, Perkan, Andrea, Pinamonti, Bruno, Pappalardo, Aniello, Berardini, Alessandra, Biagini, Elena, Saia, Francesco, Grigioni, Francesco, Rapezzi, Claudio, Sinagra, Gianfranco |
| المساهمون: | Stolfo, Davide, De Luca, Antonio, Morea, Gaetano, Merlo, Marco, Vitrella, Giancarlo, Caiffa, Thoma, Barbati, Giulia, Rakar, Serena, Korcova, Renata, Perkan, Andrea, Pinamonti, Bruno, Pappalardo, Aniello, Berardini, Alessandra, Biagini, Elena, Saia, Francesco, Grigioni, Francesco, Rapezzi, Claudio, Sinagra, Gianfranco |
| سنة النشر: | 2018 |
| المجموعة: | Università degli Studi di Ferrara: CINECA IRIS |
| مصطلحات موضوعية: | Heart failure, MitraClip, Mitral annulu, Mitral regurgitation, Cardiology and Cardiovascular Medicine |
| الوصف: | Background: Patients with heart failure (HF) and severe symptomatic functional mitral regurgitation (FMR) may benefit from MitraClip implantation. With increasing numbers of patients being treated the success of procedure becomes a key issue. We sought to investigate the pre-procedural predictors of device failure in patients with advanced HF treated with MitraClip. Methods: From April 2012 to November 2016, 76 patients with poor functional class (NYHA class III-IV) and severe left ventricular (LV) remodeling underwent MitraClip implantation at University Hospitals of Trieste and Bologna (Italy). Device failure was assessed according to MVARC criteria. Patients were subsequently followed to additionally assess the patient success after 12. months. Results: Mean age was 67±12years, the mean Log-EuroSCORE was 23.4±16.5%, and the mean LV end-diastolic volume index and ejection fraction (EF) were 112±33ml/m2and 30.6±8.9%, respectively. At short-term evaluation, device failure was observed in 22 (29%) patients. Univariate predictors of device failure were LVEF, LV and left atrial volumes and anteroposterior mitral annulus diameter. Annulus dimension (OR 1.153, 95% CI 1.002-1.327, p =0.043) and LV end-diastolic volume (OR 1.024, 95% CI 1.000-1.049, p =0.049) were the only variables independently associated with the risk of device failure at the multivariate model. Conclusions: Pre-procedural anteroposterior mitral annulus diameter accurately predicted the risk of device failure after MitraClip in the setting of advanced HF. Its assessment might aid the selection of the best candidates to percutaneous correction of FMR. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/29358003; info:eu-repo/semantics/altIdentifier/wos/WOS:000427530200045; volume:257; firstpage:182; lastpage:187; numberofpages:6; journal:INTERNATIONAL JOURNAL OF CARDIOLOGY; http://hdl.handle.net/11392/2414901; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85040617079; https://www.sciencedirect.com/science/article/pii/S0167527317366780 |
| DOI: | 10.1016/j.ijcard.2018.01.009 |
| الاتاحة: | http://hdl.handle.net/11392/2414901 https://doi.org/10.1016/j.ijcard.2018.01.009 https://www.sciencedirect.com/science/article/pii/S0167527317366780 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.EC48E2C7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.ijcard.2018.01.009 |
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