Academic Journal
Concomitant endometriosis in malignant and borderline ovarian tumours
| العنوان: | Concomitant endometriosis in malignant and borderline ovarian tumours |
|---|---|
| المؤلفون: | Engin Oral, Ovgu Aydin, Banu Aygun Kumbak, Sennur İlvan, Handan Yilmaz, Esra Tustas, Tugan Bese, Fuat Demirkiran, Macit Arvas |
| المصدر: | Journal of Obstetrics and Gynaecology, Vol 38, Iss 8, Pp 1104-1109 (2018) |
| بيانات النشر: | Taylor & Francis Group |
| سنة النشر: | 2018 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | endometriosis-associated ovarian cancer, borderline ovarian tumour, malignant ovarian tumour, endometriosis, Gynecology and obstetrics, RG1-991 |
| الوصف: | The aim of the study was to reveal the prevalence of concomitant endometriosis in malignant and borderline ovarian tumours. A retrospective analysis was performed of 530 patients with malignant ovarian tumours and 131 with borderline ovarian tumours, who underwent surgery in our hospital between 1995 and 2011. Forty-eight (7.3%) of 661 patients with malignant and borderline ovarian tumours were associated with endometriosis. Of the 48 endometriosis cases, 73% of those were atypical. Infertility was noted in 38% of patients with endometriosis-associated ovarian tumours. The most frequently endometriosis-associated subtypes were endometrioid (33%) and clear cell (18%) histologies. Of endometriosis-associated endometrioid and clear cell ovarian tumours, 70% were early stage and 60% were premenopausal. The prevalence of concomitant endometriosis in borderline tumours (12%) was found to be significantly higher than that found in the malignant ones (6%; p = .02). Of 32 endometriosis-associated malignant ovarian tumours, 69% were FIGO stages I and II. In conclusion, ovarian endometriosis is seen with both malignant and borderline ovarian tumours, the association being significant with borderline tumours. Fortunately, the endometriosis-associated malignant ovarian tumours are mostly early stage.Impact statement What is already known on this subject? Epidemiologic data suggest that endometriosis has malignant potential. However, a subgroup of women with endometriosis at a high risk for ovarian cancer is yet to be clarified. Currently, endometriosis and ovarian cancer association does not seem to have a clinical implication. What do the results of this study add? The findings of this study revealed that nearly 75% of endometriosis-associated ovarian tumours were of atypical endometriosis. Half of endometriosis-associated ovarian tumour cases were of endometrioid/clear cell histology and 70% were early-stage. Endometriosis was significantly associated with borderline ovarian tumours and the endometriosis-associated ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0144-3615 1364-6893 |
| Relation: | http://dx.doi.org/10.1080/01443615.2018.1441815; https://doaj.org/toc/0144-3615; https://doaj.org/toc/1364-6893; https://doaj.org/article/0a586052958c4eaca5e152d8fc7f1456 |
| DOI: | 10.1080/01443615.2018.1441815 |
| الاتاحة: | https://doi.org/10.1080/01443615.2018.1441815 https://doaj.org/article/0a586052958c4eaca5e152d8fc7f1456 |
| رقم الانضمام: | edsbas.EBBC7459 |
| قاعدة البيانات: | BASE |
| تدمد: | 01443615 13646893 |
|---|---|
| DOI: | 10.1080/01443615.2018.1441815 |