Academic Journal
Chronic kidney disease and adverse pregnancy outcomes: a systematic review and meta-analysis
| العنوان: | Chronic kidney disease and adverse pregnancy outcomes: a systematic review and meta-analysis |
|---|---|
| المؤلفون: | Al Khalaf, Sukainah, Bodunde, Elizabeth, Maher, Gillian M., O'Reilly, Éilis J., McCarthy, Fergus P., O'Shaughnessy, Michelle M., O'Neill, Sinéad M., Khashan, Ali S. |
| بيانات النشر: | Elsevier Inc. |
| سنة النشر: | 2021 |
| المجموعة: | University College Cork, Ireland: Cork Open Research Archive (CORA) |
| مصطلحات موضوعية: | Chronic kidney disease, Fetal outcome, Perinatal outcome, Preeclampsia pregnancy, Pregnancy outcome |
| الوصف: | Objective: Limited evidence exists on the role that the cause of chronic kidney disease plays in determining pregnancy outcomes. The aim of this systematic review and meta-analysis was to examine the association between chronic kidney disease and adverse pregnancy outcomes by the cause and severity of chronic kidney disease where reported. The protocol was registered under the International Prospective Register of Systematic Reviews (CRD42020211925). Data Sources: PubMed, Embase, and Web of Science were searched until May 24, 2021, supplemented with reference list checking. Study Eligibility Criteria: Studies that compared the pregnancy outcomes in women with or without chronic kidney disease were included. Two reviewers independently screened titles, abstracts, and full-text articles according to a priori defined inclusion criteria. Methods: Data extraction and quality appraisal were performed independently by 3 reviewers. The grading of recommendations, assessment, development, and evaluation approach was used to assess the overall certainty of the evidence. Random-effects meta-analyses were used to calculate the pooled estimates using the generic inverse variance method. The primary outcomes included preeclampsia, cesarean delivery, preterm birth (<37 weeks’ gestation), and small for gestational age babies. Results: Of 4076 citations, 31 studies were included. Prepregnancy chronic kidney disease was significantly associated with a higher odds of preeclampsia (pooled crude odds ratio, 8.13; [95% confidence interval, 4.41–15], and adjusted odds ratio, 2.58; [1.33–5.01]), cesarean delivery (adjusted odds ratio, 1.65; [1.21–2.25]), preterm birth (adjusted odds ratio, 1.73; [1.31–2.27]), and small for gestational age babies (adjusted odds ratio, 1.93; [1.06–3.52]). The association with stillbirth was not statistically significant (adjusted odds ratio, 1.67; [0.96–2.92]). Subgroup analyses indicated that different causes of chronic kidney disease might confer different risks and that the severity of chronic ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf; application/zip; application/vnd.openxmlformats-officedocument.wordprocessingml.document |
| اللغة: | English |
| تدمد: | 0002-9378 |
| Relation: | Al Khalaf, S., Bodunde, E., Maher, G. M., O'Reilly, É. J., McCarthy, F. P., O'Shaughnessy, M. M., O'Neill, S. M. and Khashan, A. S. (2021) 'Chronic kidney disease and adverse pregnancy outcomes: a systematic review and meta-analysis', American Journal of Obstetrics and Gynecology. doi:10.1016/j.ajog.2021.10.037; American Journal of Obstetrics and Gynecology; http://hdl.handle.net/10468/13111 |
| DOI: | 10.1016/j.ajog.2021.10.037 |
| الاتاحة: | http://hdl.handle.net/10468/13111 https://doi.org/10.1016/j.ajog.2021.10.037 |
| Rights: | © 2021, Elsevier Inc. All rights reserved. This manuscript version is made available under the CC BY-NC-ND 4.0 license. ; https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: | edsbas.EBB40230 |
| قاعدة البيانات: | BASE |
| تدمد: | 00029378 |
|---|---|
| DOI: | 10.1016/j.ajog.2021.10.037 |