Academic Journal
Survival analysis and mortality predictors of hospitalized severe burn victims in a Malaysian burns intensive care unit
| العنوان: | Survival analysis and mortality predictors of hospitalized severe burn victims in a Malaysian burns intensive care unit |
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| المؤلفون: | Tan Chor Lip, Henry, Tan, Jih Huei, Thomas, Mathew, Imran, Farrah-Hani, Azmah Tuan Mat, Tuan Nur’ |
| المصدر: | Burns & Trauma ; volume 7 ; ISSN 2321-3876 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2019 |
| الوصف: | Background Prognostic measures to determine burn mortality are essential in evaluating the severity of individual burn victims. This is an important process of triaging patients with high risk of mortality that may be nursed in the acute care setting. Malaysian burn research is lacking with only one publication identified which describes the epidemiology of burn victims. Therefore, the objective of this study was to go one step further and identify the predictors of burn mortality from a Malaysian burns intensive care unit (BICU) which may be used to triage patients at higher risk of death. Methods This is a retrospective cohort study of all admissions to Hospital Sultan Ismail’s BICU from January 2010 till October 2015. Admission criteria were in accordance with the American Burn Association guidelines, and risk factors of interest were recorded. Data was analyzed using simple logistic regression to determine significant predictors of mortality. Survival analysis with time to death event was performed using the Kaplan-Meier survival curve with log-rank test. Results Through the 6-year period, 393 patients were admitted with a male preponderance of 73.8%. The mean age and length of stay were 35.6 (±15.72) years and 15.3 (±18.91) days. There were 48 mortalities with an overall mortality rate of 12.2%. Significant risk factors identified on simple logistic regression were total body surface area (TBSA) > 20% (p < 0.001), inhalation injury (p < 0.001) and presence of early systemic inflammatory response syndrome (SIRS) (p < 0.001). Survival analysis using Kaplan-Meier survival curve showed similar results with TBSA > 20%, presence of SIRS, mechanical ventilation and inhalation injury which were associated with poorer survival (p < 0.001). Conclusion The predictors of mortality identified in a Malaysian BICU were TBSA > 20%, early SIRS, mechanical ventilation and inhalation injury which were associated with poorer survival outcome. The immunological response ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1186/s41038-018-0140-1 |
| DOI: | 10.1186/s41038-018-0140-1.pdf |
| DOI: | 10.1186/s41038-018-0140-1/fulltext.html |
| DOI: | 10.1186/s41038-018-0140-1/37962330/burns_v7_1_140.pdf |
| الاتاحة: | http://dx.doi.org/10.1186/s41038-018-0140-1 http://link.springer.com/content/pdf/10.1186/s41038-018-0140-1.pdf http://link.springer.com/article/10.1186/s41038-018-0140-1/fulltext.html http://academic.oup.com/burnstrauma/article-pdf/doi/10.1186/s41038-018-0140-1/37962330/burns_v7_1_140.pdf |
| Rights: | http://creativecommons.org/licenses/by-nc/4.0/ ; http://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.EBA3CC8A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s41038-018-0140-1 |
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