Academic Journal
Electrocardiographic Strain Pattern Is a Major Determinant of Rehospitalization for Heart Failure After Transcatheter Aortic Valve Replacement
| العنوان: | Electrocardiographic Strain Pattern Is a Major Determinant of Rehospitalization for Heart Failure After Transcatheter Aortic Valve Replacement |
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| المؤلفون: | Joé Heger, Antonin Trimaille, Marion Kibler, Benjamin Marchandot, Marilou Peillex, Adrien Carmona, Kensuke Matsushita, Annie Trinh, Antje Reydel, Floriane Zeyons, Hélène Petit‐Eisenmann, Laurence Jesel, Patrick Ohlmann, Olivier Morel |
| المصدر: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 3 (2021) |
| بيانات النشر: | Wiley |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | aortic stenosis, heart failure, transcutaneous aortic valve implantation, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Background Electrocardiographic strain pattern (ESP) has recently been associated with increased adverse outcome in aortic stenosis and after surgical aortic valve replacement. Our study sought to determine the impact and incremental value of ESP pattern in predicting adverse outcome after transcatheter aortic valve replacement. Methods and Results A total of 585 patients with severe aortic stenosis (mean age, 83±7 years; men, 39.8%) were enrolled for transcatheter aortic valve replacement from November 2012 to May 2018. ESP was defined as ≥1‐mm concave down‐sloping ST‐segment depression and asymmetrical T‐wave inversion in the lateral leads. The primary end points of the study were all‐cause mortality, rehospitalization for heart failure, myocardial infarction, and stroke. A total of 178 (30.4%) patients were excluded because of left bundle‐branch block (n=103) or right bundle‐branch block (n=75). Among the 407 remaining patients, 106 had ESP (26.04%). At a median follow‐up of 20.00 months (11.70–29.42 months), no impact of electric strain on overall and cardiac death could be established. By contrast, incidence of rehospitalization for heart failure was significantly higher (33/106 [31.1%] versus 33/301 [11%]; P<0.001) in patients with ESP. By multivariate analyses, ESP remained a strong predictor of rehospitalization for heart failure (hazard ratio, 2.75 [95% CI, 1.61–4.67]; P<0.001). Conclusions In patients with aortic stenosis who were eligible for transcatheter aortic valve replacement, ESP is frequent and associated with an increased risk of postinterventional heart failure regardless of preoperative left ventricular hypertrophy. ESP represents an easy, objective, reliable, and low‐cost tool to identify patients who may benefit from intensified postinterventional follow‐up. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2047-9980 |
| Relation: | https://doaj.org/toc/2047-9980; https://doaj.org/article/d21a000ecc04422eab5075a3b6621c1f |
| DOI: | 10.1161/JAHA.119.014481 |
| الاتاحة: | https://doi.org/10.1161/JAHA.119.014481 https://doaj.org/article/d21a000ecc04422eab5075a3b6621c1f |
| رقم الانضمام: | edsbas.EB65EEE6 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20479980 |
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| DOI: | 10.1161/JAHA.119.014481 |