Academic Journal
Surveillance Imaging Following Head and Neck Cancer Treatment and Microvascular Reconstruction
| العنوان: | Surveillance Imaging Following Head and Neck Cancer Treatment and Microvascular Reconstruction |
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| المؤلفون: | House, Adrian E., Zebolsky, Aaron L., Jacobs, Joanna, Likhterov, Ilya, Behr, Spencer, Glastonbury, Christine, Seth, Rahul, Heaton, Chase, Knott, Philip Daniel |
| المصدر: | The Laryngoscope ; volume 131, issue 12, page 2713-2718 ; ISSN 0023-852X 1531-4995 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2021 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Objectives/Hypothesis To assess the accuracy and utility of positron emission tomography/computed tomography (PET/CT) compared with magnetic resonance imaging (MRI) for detecting head and neck cancer (HNC) recurrence after microvascular reconstructive surgery. Study Design Retrospective cohort study. Methods Analysis of HNC patients who underwent microvascular reconstruction at a single, tertiary academic center following ablative surgery from 1998 to 2015. Forty‐six patients aged 61.4 ± 15.8 years with both PET/CT and MRI examinations were identified. Two radiologists were blinded and interpreted each imaging study. Recurrence certainty scores were determined via continuous (0–100) and Likert (“Likely” to “Unlikely”) scales, with larger values indicating a higher likelihood of recurrence. Pathologic confirmation of recurrence was confirmed in 23 patients (50%). Results Among those with primary site recurrences, mean recurrence certainty was significantly higher with PET/CT versus MRI on the continuous scale (63.9 vs. 44.4, P = .006). A receiver operating characteristic analysis for predicting primary site recurrence demonstrated a significantly larger area under the curve of 0.79 for PET/CT compared to 0.64 for MRI ( P = .044). Categorization of “Likely” primary site recurrence on PET/CT, versus MRI, had higher sensitivity (0.63 vs. 0.40), but lower specificity (0.90 vs. 1.0). MRI demonstrated higher sensitivity (1.0 vs. 0.78) at detecting regional site recurrences. Conclusion PET/CT demonstrates greater sensitivity than MRI as a surveillance tool for primary site recurrence following microvascular reconstruction where clinical evaluation is hindered by anatomical distortion. Therefore, PET/CT should be pursued as first‐line imaging, with MRI utilized for confirmation of positive imaging findings at the primary site. Level of Evidence 2 Laryngoscope , 131:2713–2718, 2021 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/lary.29700 |
| الاتاحة: | http://dx.doi.org/10.1002/lary.29700 https://onlinelibrary.wiley.com/doi/pdf/10.1002/lary.29700 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/lary.29700 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.EB2A6042 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/lary.29700 |
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