Academic Journal
Genomic and physiological mechanisms underlying skin plasticity during water to air transition in an amphibious fish
| العنوان: | Genomic and physiological mechanisms underlying skin plasticity during water to air transition in an amphibious fish |
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| المؤلفون: | Dong, Yun-wei, Blanchard, Tessa S., Noll, Angela, Vasquez, Picasso, Schmitz, Juergen, Kelly, Scott P., Wright, Patricia A., Whitehead, Andrew |
| سنة النشر: | 2020 |
| المجموعة: | Georg-August-Universität Göttingen: GoeScholar |
| الوصف: | The terrestrial radiation of vertebrates required changes in skin that resolved the dual demands of maintaining a mechanical and physiological barrier while also facilitating ion and gas transport. Using the amphibious killifish Kryptolebias marmoratus, we found that transcriptional regulation of skin morphogenesis was quickly activated upon air exposure (1h). Rapid regulation of cell-cell adhesion complexes and pathways that regulate stratum corneum formation was consistent with barrier function and mechanical reinforcement. Unique blood vessel architecture and regulation of angiogenesis likely supported cutaneous respiration. Differences in ionoregulatory transcripts and ionocyte morphology were correlated with differences in salinity acclimation and resilience to air exposure. Evolutionary analyses reinforced the adaptive importance of these mechanisms. We conclude that rapid plasticity of barrier, respiratory, and ionoregulatory functions in skin evolved to support K. marmoratus’ amphibious lifestyle; similar processes may have facilitated the terrestrial radiation of other contemporary and ancient fishes. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0022-0949 1477-9145 |
| Relation: | Deutsches Primatenzentrum; https://resolver.sub.uni-goettingen.de/purl?gro-2/115037 |
| DOI: | 10.1242/jeb.235515 |
| الاتاحة: | https://resolver.sub.uni-goettingen.de/purl?gro-2/115037 https://doi.org/10.1242/jeb.235515 |
| رقم الانضمام: | edsbas.EB25C967 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00220949 14779145 |
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| DOI: | 10.1242/jeb.235515 |