Academic Journal

Adrenal cavernous hemangioma: which correct decision making process?

التفاصيل البيبلوغرافية
العنوان: Adrenal cavernous hemangioma: which correct decision making process?
المؤلفون: AGRUSA, Antonino, ROMANO, Giorgio, DOMINGUEZ RODRIGUEZ, Ligia Juliana, Amato, G, CITARRELLA, Roberto, VERNUCCIO, Laura, DI BUONO, Giuseppe, SORCE, Vincenzo, Gulotta, L, GALIA, Massimo, MANSUETO, Pasquale, GULOTTA, Gaspare
المساهمون: Agrusa, A, Romano, G, Dominguez Rodriguez, LJ, Amato, G, Citarrella, R, Vernuccio, L, Di Buono, G, Sorce, V, Gulotta, L, Galia, M, Mansueto, P, Gulotta, G
بيانات النشر: IT
سنة النشر: 2016
المجموعة: IRIS Università degli Studi di Palermo
مصطلحات موضوعية: Adrenal cavernous hemangioma, laparoscopic adrenalectomy, laparoscopy, lapartoscopic surgery, adrenal surgery, Settore MED/09 - Medicina Interna, Settore MED/18 - Chirurgia Generale, Settore MED/13 - Endocrinologia
الوصف: Introduction: Cavernous hemangioma of the adrenal gland is a rare benign tumor characterized by the presence of blood-fil- led, dilated vascular spaces. These adrenal masses are usually non-functioning and the patients have no symptoms so the diagnosis is incidental. Methods: We performed a systematic literature review for all articles published until April 2015. The initial search identified 98 publications. We considered some characteristics: the mean age of the patients at diagnosis was 59 years (range 19 - 84); there were approximately 1.7 times more female patients than male patients; mean diameter of the lesions was 10.3 cm (range 2 - 25). Surgical treatment was more often open with midline or subcostal incision. Results: From literature analysis we know that small adrenal hemangiomas are usually asymptomatic. Only four patients in our literature review show endocrinologic disturbances with three cases of subclinical Cushing’s syndrome and a case of hyperaldo- steronism. The pre-operative radiologic features play a fundamental role for correct surgical approach. On enhanced Computed Tomography (CT) scan adrenal hemangiomas tend to be heterogeneous, hypodense lesions with high-density rim of tissue at the periphery. On Magnetic Resonance Imaging (MRI) common findings associated with adrenal hemangiomas are hypointense inhomo- geneous masses with central hyperintensity on T1 images and a high intensity peripheral rim on T2 images due to hemorrhage or necrosis. Conclusion: Laparoscopic adrenalectomy is considered the standard treatment in case of benign lesions. Some authors sugge- st that the main limitation during laparoscopic dissection for large and potentially malign adrenal tumors is incomplete resection and capsular disruption with increased risk of local recurrence and intra-abdominal neoplastic dissemination. We recommend for these patients an integrated multidisciplinary approach that considers endocrine studies, preoperative radiologic findings and the expe- rience of surgical team.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000375338000018; volume:32; issue:2; firstpage:385; lastpage:389; numberofpages:5; journal:ACTA MEDICA MEDITERRANEA; http://hdl.handle.net/10447/177822
DOI: 10.19193/0393-6384_2016_2_58
الاتاحة: http://hdl.handle.net/10447/177822
https://doi.org/10.19193/0393-6384_2016_2_58
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.EAD8AFD0
قاعدة البيانات: BASE
الوصف
DOI:10.19193/0393-6384_2016_2_58