Academic Journal

A Comparative Analysis of Morphology and Dimensions of Functional Blebs following PRESERFLO-Microshunt and XEN-Gel-Stent, a Study Using Anterior Segment OCT

التفاصيل البيبلوغرافية
العنوان: A Comparative Analysis of Morphology and Dimensions of Functional Blebs following PRESERFLO-Microshunt and XEN-Gel-Stent, a Study Using Anterior Segment OCT
المؤلفون: Hasan, Somar M., Theilig, Theresa, Papadimitriou, Menelaos, Meller, Daniel
المساهمون: Lanza, Michele, Ruíz-Moreno, José María
سنة النشر: 2023
المجموعة: Digital Library Thüringen
مصطلحات موضوعية: article, ScholarlyArticle, ddc:610, glaucoma filtering surgery, minimally invasive glaucoma surgery, bleb surgery, optical coherence tomography, bleb morphology, PRESERFLO Microshunt, XEN Gel Stent
الوصف: Evaluation of bleb morphology is a vital part of successful filtration glaucoma surgery. The PRESERFLO-MicroShunt (PRESERFLO) and XEN-Gel-Stent (XEN) are drainage devices implanted using different surgical approaches (ab externo and ab interno, respectively), potentially resulting in distinct bleb morphology. Understanding these morphological differences is essential for postoperative care. In this study, we retrospectively examined functioning blebs following PRESERFLO and XEN implantation using high-resolution anterior segment OCT imaging. Qualitative assessment utilizing the Jenaer Bleb Grading System and quantitative assessment measuring 12 parameters representing bleb dimensions were conducted, and the results were compared between the two groups. A total of 80 eyes from 80 patients were included (41 after PRESERFLO, 39 after XEN). Functioning blebs following PRESERFLO exhibited a higher frequency of hyperreflective tenon changes compared to XEN (31.7% vs. 10.3%, respectively, p = 0.02) and a lower frequency of cavernous changes (17.1% vs. 35.9%, p = 0.05). Additionally, PRESERFLO blebs showed a higher frequency of visible episcleral lakes (92.7% vs. 30.8%, p < 0.001). Furthermore, PRESERFLO blebs demonstrated larger height (2.13 ± 0.5 vs. 1.85 ± 0.6 mm, p = 0.03), width (10.31 ± 2.3 vs. 9.1 ± 2.3 mm, p = 0.02), length (9.13 ± 1.8 vs. 8.24 ± 1.9 mm, p = 0.04), posterior location relative to the limbus (6.21 ± 1.2 vs. 5.21 ± 1.8 mm, p = 0.005), and a thicker bleb wall (1.60 ± 0.5 vs. 1.1 ± 0.4 mm, p = 0.004). Functioning blebs following PRESERFLO and XEN displayed morphological distinctions, likely attributed to variations in surgical techniques (ab externo vs. ab interno) and stent dimensions. These morphological differences should be taken into consideration when evaluating blebs, as they could impact assessments of bleb functionality and influence decisions regarding postoperative interventions.
نوع الوثيقة: article in journal/newspaper
وصف الملف: 12 Seiten
اللغة: English
Relation: Diagnostics -- 2075-4418 -- http://uri.gbv.de/document/gvk:ppn:718627814 -- 2662336-5 -- http://www.mdpi.com/journal/diagnostics -- https://www.ncbi.nlm.nih.gov/pmc/journals/2841/ -- http://www.bibliothek.uni-regensburg.de/ezeit/?2662336; https://doi.org/10.3390/diagnostics13142318
DOI: 10.3390/diagnostics13142318
الاتاحة: https://doi.org/10.3390/diagnostics13142318
https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-20230808-160633-004
https://www.db-thueringen.de/receive/dbt_mods_00058383
https://www.db-thueringen.de/servlets/MCRFileNodeServlet/dbt_derivate_00061133/diagnostics-13-02318-v2.pdf
Rights: https://creativecommons.org/licenses/by/4.0/ ; public ; info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.EAC05653
قاعدة البيانات: BASE
الوصف
DOI:10.3390/diagnostics13142318