Academic Journal
A distal CCAAT/NUCLEAR FACTOR Y complex promotes chromatin looping at the FLOWERING LOCUS T promoter and regulates the timing of flowering in Arabidopsis
| العنوان: | A distal CCAAT/NUCLEAR FACTOR Y complex promotes chromatin looping at the FLOWERING LOCUS T promoter and regulates the timing of flowering in Arabidopsis |
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| المؤلفون: | S. Cao, R. W. Kumimoto, B. F. Holt, N. Gnesutta, A.M. Calogero, R. Mantovani |
| المساهمون: | S. Cao, R.W. Kumimoto, N. Gnesutta, A.M. Calogero, R. Mantovani, B.F. Holt |
| بيانات النشر: | American Society of Plant Biologists |
| سنة النشر: | 2014 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | Settore BIO/18 - Genetica, Settore BIO/10 - Biochimica |
| الوصف: | For many plant species, reproductive success relies on the proper timing of flowering, and photoperiod provides a key environmental input. Photoperiod-dependent flowering depends on timely expression of FLOWERING LOCUS T (FT); however, the coordination of various cis-regulatory elements in the FT promoter is not well understood. Here, we provide evidence that long-distance chromatin loops bring distal enhancer elements into close association with the proximal promoter elements bound by CONSTANS (CO). Additionally, we show that NUCLEAR FACTOR Y (NF-Y) binds a CCAAT box in the distal enhancer element and that CCAAT disruption dramatically reduces FT promoter activity. Thus, we propose the recruitment model of photoperiod-dependent flowering where NF-Y complexes, bound at the FT distal enhancer element, help recruit CO to proximal cis-regulatory elements and initiate the transition to reproductive growth. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/24610724; info:eu-repo/semantics/altIdentifier/wos/WOS:000334932700016; volume:26; issue:3; firstpage:1009; lastpage:1017; numberofpages:9; journal:PLANT CELL; http://hdl.handle.net/2434/233806; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84899154279 |
| DOI: | 10.1105/tpc.113.120352 |
| الاتاحة: | http://hdl.handle.net/2434/233806 https://doi.org/10.1105/tpc.113.120352 |
| رقم الانضمام: | edsbas.EA1F25C4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1105/tpc.113.120352 |
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