Academic Journal

Mesenchymal Stem Cell Therapy in the Management of Cerebral Palsy (CP): A Promising Intervention for Functional Improvement

التفاصيل البيبلوغرافية
العنوان: Mesenchymal Stem Cell Therapy in the Management of Cerebral Palsy (CP): A Promising Intervention for Functional Improvement
المؤلفون: Pada Vinski, Deby Susanti, Quintosa, Jaime Rodriguez, Schroeter, Trofimova, Svetlana, Jovanovic, Stevan, Nugroho, Andi Kurniawan, Vinski, Natasha Cinta, Hardjo, Marhaen
المصدر: International Journal of Social Health; Vol. 3 No. 6 (2024): International Journal of Social Health ; 363-369 ; 2984-7079 ; 10.58860/ijsh.v3i06
بيانات النشر: Ravine Publisher
سنة النشر: 2024
مصطلحات موضوعية: Cell Therapyhyg, Mesenchymal Stem, Management of Cerebral
الوصف: Cerebral palsy (CP) encompasses a diverse range of motor disorders stemming from early-life brain injury or abnormal development. Despite therapeutic advancements, novel interventions are needed to enhance outcomes for CP patients. Mesenchymal stem cells (MSCs) derived from umbilical cord blood offer promising therapeutic potential due to their immunomodulatory, anti-inflammatory, and neuroprotective properties. This case study evaluates the efficacy of cord blood MSC therapy in treating CP, utilizing patient care records as the primary data source. Studies meeting predefined inclusion criteria were analyzed, focusing on outcomes such as motor function, spasticity, cognition, and quality of life. Initial findings indicate a significant positive impact of MSC therapy on motor function, alongside improvements in spasticity, cognition, and quality of life across various studies. Subgroup analyses underscored differences in treatment protocols, dosages, administration routes, and follow-up durations, underscoring the need for standardized approaches in future research. Overall, this systematic review and meta-analysis provide compelling evidence supporting the safety and effectiveness of cord blood MSC therapy for CP. Future randomized controlled trials with larger cohorts and extended follow-up periods are necessary to validate these findings and establish optimal treatment protocols.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf; text/html
اللغة: English
Relation: https://ijsh.ph/index.php/rp/article/view/204/634; https://ijsh.ph/index.php/rp/article/view/204/635; https://ijsh.ph/index.php/rp/article/view/204
DOI: 10.58860/ijsh.v3i6.204
الاتاحة: https://ijsh.ph/index.php/rp/article/view/204
https://doi.org/10.58860/ijsh.v3i6.204
Rights: Copyright (c) 2024 Deby Susanti Pada Vinski, Jaime Rodriguez Quintosa, Schroeter, Svetlana Trofimova, Stevan Jovanovic, Andi Kurniawan Nugroho, Natasha Cinta Vinski, Marhaen Hardjo ; https://creativecommons.org/licenses/by-sa/4.0
رقم الانضمام: edsbas.E9ED9175
قاعدة البيانات: BASE