Academic Journal
Skin care interventions in infants for preventing eczema and food allergy
| العنوان: | Skin care interventions in infants for preventing eczema and food allergy |
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| المؤلفون: | Kelleher, Maeve M., Cro, Suzie, Cornelius, Victoria, Lodrup Carlsen, Karin C., Skjerven, H�vard O., Rehbinder, Eva M, Lowe, Adrian J., Dissanayake, Eishika, Shimojo, Naoki, Yonezawa, Kaori, Ohya, Yukihiro, Yamamoto-Hanada, Kiwako, Morita, Kumiko, Axon, Emma, Surber, Christian, Cork, Michael, Cooke, Alison, Tran, Lien, Van Vogt, Eleanor, Schmitt, Jochen, Weidinger, Stephan, McClanahan, Danielle, Simpson, Eric, Duley, Lelia, Askie, Lisa M., Chalmers, Joanne R., Williams, Hywel C., Boyle, Robert J. |
| المساهمون: | Cochrane Skin Group |
| بيانات النشر: | Wiley |
| سنة النشر: | 2021 |
| المجموعة: | University of Nottingham: Repository@Nottingham |
| الوصف: | BackgroundEczema and food allergy are common health conditions that usually begin in early childhood and often occur together in the same people. They can be associated with an impaired skin barrier in early infancy. It is unclear whether trying to prevent or reverse an impaired skin barrier soon after birth is effective in preventing eczema or food allergy.ObjectivesPrimary objectiveTo assess effects of skin care interventions, such as emollients, for primary prevention of eczema and food allergy in infantsSecondary objectiveTo identify features of study populations such as age, hereditary risk, and adherence to interventions that are associated withthe greatest treatment benefit or harm for both eczema and food allergy.Search methodsWe searched the following databases up to July 2020: Cochrane Skin Specialised Register, CENTRAL, MEDLINE, and Embase. We searched two trials registers and checked reference lists of included studies and relevant systematic reviews for further references to relevant randomised controlled trials (RCTs). We contacted field experts to identify planned trials and to seek information about unpublished or incomplete trials.Selection criteriaRCTs of skin care interventions that could potentially enhance skin barrier function, reduce dryness, or reduce subclinical inflammation in healthy term (> 37 weeks) infants (0 to 12 months) without pre‐existing diagnosis of eczema, food allergy, or other skin condition were included. Comparison was standard care in the locality or no treatment. Types of skin care interventions included moisturisers/emollients; bathing products; advice regarding reducing soap exposure and bathing frequency; and use of water softeners. No minimum follow‐up was required.Data collection and analysisThis is a prospective individual participant data (IPD) meta‐analysis. We used standard Cochrane methodological procedures, and primary analyses used the IPD dataset. Primary outcomes were cumulative incidence of eczema and cumulative incidence of immunoglobulin ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://nottingham-repository.worktribe.com/output/5311218; Cochrane Database of Systematic Reviews; Volume 2021; Issue 2 |
| DOI: | 10.1002/14651858.cd013534.pub2 |
| الاتاحة: | https://doi.org/10.1002/14651858.cd013534.pub2 https://nottingham-repository.worktribe.com/file/5311218/1/Skin%20care%20interventions%20in%20infants https://nottingham-repository.worktribe.com/output/5311218 |
| Rights: | openAccess |
| رقم الانضمام: | edsbas.E6E85ED3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/14651858.cd013534.pub2 |
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