Academic Journal
Free Flap microvascular pharyngeal closure results in improved dysphagia-specific quality of life following total laryngectomy
| العنوان: | Free Flap microvascular pharyngeal closure results in improved dysphagia-specific quality of life following total laryngectomy |
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| المؤلفون: | Cleere, Eoin F., Mamdouh, Sherif, Devoy-Flood, Emma, O’Callaghan, Marie-Therese, Martin, Fiachra, O’Sullivan, John B., Shine, Neville, O’Neill, James P. |
| المساهمون: | Royal College of Surgeons in Ireland |
| المصدر: | European Journal of Plastic Surgery ; volume 45, issue 3, page 399-407 ; ISSN 1435-0130 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2021 |
| الوصف: | Background Total laryngectomy (TL) as either a primary or salvage treatment strategy remains an effective oncologic operation in the management of laryngeal cancer. Dysphagia is the most common complication following TL and this has a significant impact on patients’ quality of life (QOL). Following removal of the larynx, a number of pharyngeal closure techniques exist. We aimed to evaluate the effect pharyngeal closure techniques have on dysphagia-specific QOL postoperatively. Methods We retrospectively reviewed patients who had undergone TL at our institution (2014–2019). Patients alive at the time of study were invited to complete the MD Anderson Dysphagia Inventory (MDADI). Outcomes were compared among Primary Closure (PC), Pedicled Pectoralis Major Myocutaneous Flap (PMMF) and Free Flap (FF) closure groups. Results There were 27 patients identified for inclusion. Eight patients (30%) underwent PC, 10 patients (37%) had PMMF-assisted closure and 9 patients (33%) underwent FF-assisted closure. Patients within the FF group scored consistently higher MDADI scores across all subscales (emotional, functional, physical, global) as well as composite MDADI score in comparison to the PC and PMMF groups. FF closure was associated with a reduced inpatient length of stay (LOS). Additionally, no significant differences in postoperative morbidity including rates of pharyngo-cutaneous fistula (PCF) were observed between groups. Conclusions We now advocate FF closure for our patients following salvage TL due to the improved dysphagia-specific QOL, reduced inpatient LOS and lack of additional surgical morbidity. Level of evidence, Level III, therapeutic/prognostic study. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1007/s00238-021-01893-3 |
| DOI: | 10.1007/s00238-021-01893-3.pdf |
| DOI: | 10.1007/s00238-021-01893-3/fulltext.html |
| الاتاحة: | http://dx.doi.org/10.1007/s00238-021-01893-3 https://link.springer.com/content/pdf/10.1007/s00238-021-01893-3.pdf https://link.springer.com/article/10.1007/s00238-021-01893-3/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.E6D9596C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00238-021-01893-3 |
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