Academic Journal
Optimization of a customized simultaneous algebraic reconstruction technique algorithm for phase-contrast breast computed tomography
| العنوان: | Optimization of a customized simultaneous algebraic reconstruction technique algorithm for phase-contrast breast computed tomography |
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| المؤلفون: | Donato, S, Brombal, L, Arana Peña, L M, Arfelli, F, Contillo, A, Delogu, P, Di Lillo, F, Di Trapani, V, Fanti, V, Longo, R, Oliva, P, Rigon, L, Stori, L, Tromba, G, Golosio, B |
| المساهمون: | Donato, S, Brombal, L, Arana Peña, L M, Arfelli, F, Contillo, A, Delogu, P, Di Lillo, F, Di Trapani, V, Fanti, V, Longo, R, Oliva, P, Rigon, L, Stori, L, Tromba, G, Golosio, B |
| سنة النشر: | 2022 |
| المجموعة: | Università degli studi di Trieste: ArTS (Archivio della ricerca di Trieste) |
| مصطلحات موضوعية: | breast CT, iterative reconstruction algorithm, machine learning, propagation-based phase-contrast imaging, synchrotron radiation, Algorithm, Tellurium, Tomography, X-Ray Computed, Cadmium Compound, Quantum Dots |
| الوصف: | Objective. To introduce the optimization of a customized GPU-based simultaneous algebraic reconstruction technique (cSART) in the field of phase-contrast breast computed tomography (bCT). The presented algorithm features a 3D bilateral regularization filter that can be tuned to yield optimal performance for clinical image visualization and tissues segmentation. Approach. Acquisitions of a dedicated test object and a breast specimen were performed at Elettra, the Italian synchrotron radiation (SR) facility (Trieste, Italy) using a large area CdTe single-photon counting detector. Tomographic images were obtained at 5 mGy of mean glandular dose, with a 32 keV monochromatic x-ray beam in the free-space propagation mode. Three independent algorithms parameters were optimized by using contrast-to-noise ratio (CNR), spatial resolution, and noise texture metrics. The results obtained with the cSART algorithm were compared with conventional SART and filtered back projection (FBP) reconstructions. Image segmentation was performed both with gray scale-based and supervised machine-learning approaches. Main results. Compared to conventional FBP reconstructions, results indicate that the proposed algorithm can yield images with a higher CNR (by 35% or more), retaining a high spatial resolution while preserving their textural properties. Alternatively, at the cost of an increased image 'patchiness', the cSART can be tuned to achieve a high-quality tissue segmentation, suggesting the possibility of performing an accurate glandularity estimation potentially of use in the realization of realistic 3D breast models starting from low radiation dose images. Significance. The study indicates that dedicated iterative reconstruction techniques could provide significant advantages in phase-contrast bCT imaging. The proposed algorithm offers great flexibility in terms of image reconstruction optimization, either toward diagnostic evaluation or image segmentation. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/35395648; info:eu-repo/semantics/altIdentifier/wos/WOS:000787098900001; volume:67; issue:9; firstpage:"-"; lastpage:"-"; numberofpages:15; journal:PHYSICS IN MEDICINE AND BIOLOGY; https://hdl.handle.net/11368/3025194; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85129638034; https://iopscience.iop.org/article/10.1088/1361-6560/ac65d4 |
| DOI: | 10.1088/1361-6560/ac65d4 |
| الاتاحة: | https://hdl.handle.net/11368/3025194 https://doi.org/10.1088/1361-6560/ac65d4 https://iopscience.iop.org/article/10.1088/1361-6560/ac65d4 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.E52BE6BF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1088/1361-6560/ac65d4 |
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