Academic Journal
Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities Study
| العنوان: | Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities Study |
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| المؤلفون: | Palta, P., Sharrett, A.R., Deal, J.A., Evenson, K.R., Gabriel, K.P., Folsom, A.R., Gross, A.L., Windham, B.G., Knopman, D., Mosley, T.H., Heiss, G. |
| المصدر: | Alzheimer's and Dementia, 15(2) |
| بيانات النشر: | Elsevier Inc. |
| سنة النشر: | 2019 |
| المجموعة: | Carolina Digital Repository (UNC - University of North Carolina) |
| مصطلحات موضوعية: | Cognitive decline, Epidemiology, Dementia, Cohort study, Physical activity |
| الوصف: | Introduction: We tested the hypotheses that higher levels of and persistence of midlife leisure-time physical activity (LTPA) are associated long-term with lower cognitive decline and less incident dementia. Methods: A total of 10,705 participants (mean age: 60 years) had LTPA (no, low, middle, or high) measured in 1987-1989 and 1993-1995. LTPA was assessed in relation to incident dementia and 14-year change in general cognitive performance. Results: Over a median follow-up of 17.4 years, 1063 dementia cases were observed. Compared with no LTPA, high LTPA in midlife was associated with lower incidence of dementia (hazard ratio [95% confidence interval], 0.71 [0.61, 0.86]) and lower declines in general cognitive performance (−0.07 standard deviation difference [−0.12 to −0.04]). These associations were stronger when measured against persistence of midlife LTPA over 6 years. Discussion: LTPA is a readily modifiable factor associated inversely with long-term dementia incidence and cognitive decline. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://doi.org/10.17615/ewya-jy91; https://cdr.lib.unc.edu/downloads/xd07h300x?file=thumbnail; https://cdr.lib.unc.edu/downloads/xd07h300x |
| DOI: | 10.17615/ewya-jy91 |
| الاتاحة: | https://doi.org/10.17615/ewya-jy91 https://cdr.lib.unc.edu/downloads/xd07h300x?file=thumbnail https://cdr.lib.unc.edu/downloads/xd07h300x |
| Rights: | http://rightsstatements.org/vocab/InC/1.0/ |
| رقم الانضمام: | edsbas.E4522F81 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17615/ewya-jy91 |
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