التفاصيل البيبلوغرافية
| العنوان: |
Perubahan Kadar Hormon Tiroid pada Penderita Sindroma Nefrotik |
| المؤلفون: |
Asripurwanti, Asripurwanti, Samad,, Samad, Koesnadi, Lydia, Rochmanaji, W., Susanto, Rudy |
| المصدر: |
MEDIA MEDIKA INDONESIANA; 2008:MMI Volume 43 Issue 2 Year 2008; 95-102 ; 0126-1762 |
| بيانات النشر: |
MEDIA MEDIKA INDONESIANA |
| سنة النشر: |
2012 |
| المجموعة: |
Universitas Diponegoro: Undip E-Journal System (UEJS) Portal |
| مصطلحات موضوعية: |
Thyroid hormone, TSH, T4, Nephrotic Syndrome |
| الوصف: |
Thyroid hormones levels in nephrotic syndromeBackground: Nephrotic syndrome is one of the most found kidney disease. A great part (>99%) of circulating thyroid hormones were bound to proteins, thus derangements of blood proteins in nephrotic syndrome are potential to disturb thyroid hormones levels. This study was aimed to compare thyroid hormones levels changes in childhood Nephrotic Syndrome before and after remission.Method: Thirty four nephrotic syndrome patients studied on Department of pediatric of Dr. Kariadi Hospital, Semarang between April 1995 to June 1996 were for albumin, cholesterol, thyroid and thyroid stimulating hormone levels before and after remission and were tested with Wilcoxon signed rank test. The correlation between albumin and thyroxin levels before and after remission. were analyzed with Spearman correlation test.Results: T4 level before remission was 26.89±16.12 nmol/L, TSH 9.36±5.51 IU/ml, and after remission T4 106.63±28.02 nmol/L,TSH 1.78±1.91 μIU/mL. There were significant changes of thyroid hormones levels before and after remission (z=5.09; p=0.000). There were positive correlation between blood protein (albumin) level and thyroid hormone (T4) level in nephrotic syndrome before remission (r=0.51; p=0.000) and after remission (r=0.38; p=0.004). A great proportion of nephrotic syndrome patients, suffered from hypothyroidism and return to euthyroid after remission.Conclusions: Thyroid hormone levels changed during the course of nephrotic syndrome.Keyword : Thyroid hormone, TSH, T4, Nephrotic SyndromeABSTRAKLatar belakang : Sindroma nefrotik merupakan salah satu penyakit ginjal yang terbanyak ditemukan. Hormon tiroid beredar dalam darah berikatan dengan protein, sehingga pada gangguan kadar protein yang berat seperti pada sindroma nefrotik berpotensi mengganggu hormon tiroid. Penelitian ini bertujuan untuk mempelajari perubahan kadar hormon tiroid pada penderita sindroma nefrotik anak sebelum dan sesudah remisi.Metoda : Tiga puluh empat penderita sindroma nefrotik yang dirawat di ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| Relation: |
https://ejournal.undip.ac.id/index.php/mmi/article/view/3824/3508; https://ejournal.undip.ac.id/index.php/mmi/article/view/3824 |
| الاتاحة: |
https://ejournal.undip.ac.id/index.php/mmi/article/view/3824 |
| رقم الانضمام: |
edsbas.E41C1972 |
| قاعدة البيانات: |
BASE |