التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of the ultrastructural and in vitro flow properties of the PreserFlo® microShunt |
| المؤلفون: |
Barberá, Marta Ibarz, Bragard, Jean, Fernández, laura Morales, Rivero, Pedro Tañá, de Liaño, Rosario Gomez, Guezala, Miguel Teus |
| المصدر: |
Acta Ophthalmologica ; volume 100, issue S267 ; ISSN 1755-375X 1755-3768 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2022 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Purpose The purpose of this study was to measure the luminal diameter of the PreserFlo ® microshunt and to calculate the theoretical resistance to flow for comparison with the outcomes of the in vitro flow testing of this device. Methods The PreserFlo ® was designed to control the flow of aqueous humor by means of its length and width according to the Hagen‐Poiseuille equation. Scanning electron microscopy (SEM) was performed to measure the internal lumen of the tube and flow testing was carried out using a constant gravity‐flow test. Results The SEM images of the PreserFlo ® implant showed that the luminal diameter measured 63.6 x 70.5 μm. The theoretical calculation of the resistance to flow (R) for an aqueous humor viscosity of 0.7185 was 1.3 mmHg/μL/min. Assuming a constant aqueous humor flow of 2 μL/min, the calculated pressure differential (△p) across the device was 2.6 mmHg. The experimental gravity‐flow test showed that the theoretical flow (Qtheo) and the in vitro flow (Qexp, 15.75 g/24 h) were consistent. Conclusions The internal diameter of the PreserFlo ® implant measured by SEM fits the dimensions described by the manufacturer. The experimental and theoretical flow testing showed that the pressure drop across this device is lower than the pressure required to avoid numerical hypotony. References 1. Ibarz Barberá M, Morales Fernández L, Tañá Rivero P, Gómez de Liaño R, Teus, MA (2021), Anterior‐segment optical coherence tomography of filtering blebs in the early postoperative period of ab externo SIBS microshunt implantation with mitomycin C: Morphological analysis and correlation with intraocular pressure reduction. Acta Ophthalmol. https://doi.org/10.1111/aos.14863 2. Sheybani A, Reitsamer H, Ahmed II. Fluid Dynamics of a Novel Micro‐Fistula Implant for the Surgical Treatment of Glaucoma. Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4789–95. 3. Pinchuk L, Riss I, Batlle JF, Kato YP, Martin JB, Arrieta E, Palmberg P, Parrish RK 2nd, Weber BA, Kwon Y, Parel JM. The development of a micro‐shunt ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/j.1755-3768.2022.114 |
| الاتاحة: |
http://dx.doi.org/10.1111/j.1755-3768.2022.114 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: |
edsbas.E351248A |
| قاعدة البيانات: |
BASE |