Academic Journal
The multiple lifestyle modification for patients with prehypertension and hypertension patients: a systematic review protocol
| العنوان: | The multiple lifestyle modification for patients with prehypertension and hypertension patients: a systematic review protocol |
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| المؤلفون: | Li, Juan, Zheng, Hui, Du, Huai-bin, Tian, Xiao-ping, Jiang, Yi-jing, Zhang, Shao-lan, Kang, Yu, Li, Xiang, Chen, Jie, Lu, Chao, Lai, Zhen-hong, Liang, Fan-rong |
| المصدر: | BMJ Open ; volume 4, issue 8, page e004920 ; ISSN 2044-6055 2044-6055 |
| بيانات النشر: | BMJ |
| سنة النشر: | 2014 |
| الوصف: | Introduction The objective of this systematic review is to investigate the effectiveness, efficacy and safety of multiple concomitant lifestyle modification therapies for patients with hypertension or prehypertension. Methods and analysis Electronic searches will be performed in the Cochrane Library, OVID, EMBASE, etc, along with manual searches in the reference lists of relevant papers found during electronic search. We will identify eligible randomised controlled trials utilising multiple lifestyle modifications to lower blood pressure. The control could be drug therapy, single lifestyle change or no intervention. Changes in systolic blood pressure and diastolic blood pressure constitute primary end points, and secondary end points include the number of patients meeting the office target blood pressure, the number of patients reporting microvascular or macrovascular complications, etc. We will extract descriptive, methodological and efficacy data from identified randomised controlled trials (RCTs). We will calculate the relative risk for proportion of patients with a normal blood pressure in the experimental group. Dichotomous data will be analysed using risk difference and continuous data using weighted mean differences, both with 95% CI. We will use the χ 2 test and the I 2 statistic to assess heterogeneity. We will use the fixed effects model to compute the efficacy unless there is evidence of heterogeneity. If heterogeneity of effect size persists with respect to blood pressure change, further metaregression will be performed within groups. We will examine the potential for publication bias by using a funnel plot. Dissemination We will synthesise results from RCTs which provide more precise and accurate information on the effect of multiple lifestyle changes on blood pressure. The results of this review will increase the understanding of multiple lifestyle modifications for patients with hypertension or prehypertension. Trail registration number Our protocol is registered on PROSPERO (CRD42013006476), ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1136/bmjopen-2014-004920 |
| الاتاحة: | http://dx.doi.org/10.1136/bmjopen-2014-004920 https://syndication.highwire.org/content/doi/10.1136/bmjopen-2014-004920 |
| رقم الانضمام: | edsbas.E2F8D6AB |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/bmjopen-2014-004920 |
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