Academic Journal
Research progress of NF-κB signaling pathway and thrombosis
| العنوان: | Research progress of NF-κB signaling pathway and thrombosis |
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| المؤلفون: | Wang, Zilong, Fang, Chucun, Yao, Mengting, Wu, Dongwen, Chen, Maga, Guo, Tianting, Mo, Jianwen |
| المساهمون: | National Natural Science Foundation of China, Natural Science Foundation of Jiangxi Province |
| المصدر: | Frontiers in Immunology ; volume 14 ; ISSN 1664-3224 |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2023 |
| المجموعة: | Frontiers (Publisher - via CrossRef) |
| الوصف: | Venous thromboembolism is a very common and costly health problem. Deep-vein thrombosis (DVT) can cause permanent damage to the venous system and lead to swelling, ulceration, gangrene, and other symptoms in the affected limb. In addition, more than half of the embolus of pulmonary embolism comes from venous thrombosis, which is the most serious cause of death, second only to ischemic heart disease and stroke patients. It can be seen that deep-vein thrombosis has become a serious disease affecting human health. In recent years, with the deepening of research, inflammatory response is considered to be an important pathway to trigger venous thromboembolism, in which the transcription factor NF-κB is the central medium of inflammation, and the NF-κB signaling pathway can regulate the pro-inflammatory and coagulation response. Thus, to explore the mechanism and make use of it may provide new solutions for the prevention and treatment of thrombosis. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| DOI: | 10.3389/fimmu.2023.1257988 |
| DOI: | 10.3389/fimmu.2023.1257988/full |
| الاتاحة: | http://dx.doi.org/10.3389/fimmu.2023.1257988 https://www.frontiersin.org/articles/10.3389/fimmu.2023.1257988/full |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.E2B3E6F3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fimmu.2023.1257988 |
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