التفاصيل البيبلوغرافية
| العنوان: |
Fig S1.pdf |
| المؤلفون: |
Mauricio Ostrosky-Frid (10104479), María Chávez-Canales (10104481), Jinwei Zhang (462455), Olena Andrukhova (183123), Eduardo R. Argaiz (10104498), Fernando Lerdo-de-Tejada (10104486), Adrián Rafael Murillo-de-Ozores (8660322), Andrea Sanchez-Navarro (8660274), Lorena Rojas-Vega (10104488), Norma A. Bobadilla (203727), Norma Vazquez (10104491), MARIA CASTANEDA-BUENO (10104388), Dario R. Alessi (157506), Gerardo Gamba (9568811) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Physiology, KS-WNK1, WNK1, KIDNEY |
| الوصف: |
Figure S1. Targeting strategy for the generation of KLHL3 +/R528H mice. A) The diagram shows the KLHL3 genomic locus, the linearized targeting vector, and the targeted allele before and after Flp-mediated recombination. The mutated bases and amino acid residue substitution are depicted below. B) Results of genotyping with primers P1 and P2 (see sequence in main text). Primers bind within intron 15 and amplify the segment in which the single FRT site that remains after Flp-mediated recombination is located. Thus, the product amplified from the wild type allele is 75 bp shorter than the product amplified from the KI allele. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Fig_S1_pdf/13721791 |
| DOI: |
10.6084/m9.figshare.13721791.v1 |
| الاتاحة: |
https://doi.org/10.6084/m9.figshare.13721791.v1 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.E10B013C |
| قاعدة البيانات: |
BASE |