Academic Journal

ESBL-producing Escherichia coli and Klebsiella pneumoniae from health-care institutions in Mexico

التفاصيل البيبلوغرافية
العنوان: ESBL-producing Escherichia coli and Klebsiella pneumoniae from health-care institutions in Mexico
المؤلفون: Viridiana Gallegos-Miranda (9920803), Ulises Garza-Ramos (473584), Enrique Bolado-Martínez (9920806), Moisés Navarro-Navarro (9920809), Katya Rocío Félix-Murray (9920812), Maria del Carmen Candia-Plata (9920815), Guillermina Sanchez-Martinez (9920818), Josefina Dúran-Bedolla (9920821), Jesús Silva-Sánchez (325352)
سنة النشر: 2020
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Medicine, Microbiology, Molecular Biology, Ecology, Cancer, Infectious Diseases, Virology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, β-lactamases, quinolone resistance, PMQR, PFGE, aac(6´)-Ib-cr, qnrB, qnrS
الوصف: We investigated the phenotypic and molecular characteristics of Extended-Spectrum-β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae clinical isolates from four health-care institutions in Hermosillo, Sonora, Mexico. ESBL-producing isolates were collected from February to August 2016. The prevalence of ESBL-producing E. coli and K. pneumoniae was 11.9 and 8.7%, respectively. High dissemination of resistance to ciprofloxacin (88%), trimethoprim/sulfamethoxazole (72%) and aminoglycosides (59%) were detected, as well as susceptibility to meropenem, amikacin and tigecycline. The ESBL found variants were CTX-M-1 (88%) and CTX-M-9 (5%). The plasmid-mediated quinolone resistance ( PMQR ) gene aac(6 ´ )-Ib-cr was identified in 62% of a representative sample, whereas the qnrB and qnrS genes were detected in 49% of the isolates. PFGE analyses detected many unrelated clones among the hospital or community isolates. A constant programme of epidemiological surveillance is recommended to understand the dynamics of bacterial resistance to both cephalosporin as well as the fluoroquinolone family of antibiotics.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
Relation: https://figshare.com/articles/journal_contribution/ESBL-producing_i_Escherichia_coli_i_and_i_Klebsiella_pneumoniae_i_from_health-care_institutions_in_Mexico/13490953
DOI: 10.6084/m9.figshare.13490953.v1
الاتاحة: https://doi.org/10.6084/m9.figshare.13490953.v1
Rights: CC BY 4.0
رقم الانضمام: edsbas.E0D626CC
قاعدة البيانات: BASE
الوصف
DOI:10.6084/m9.figshare.13490953.v1