Academic Journal
Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation
| العنوان: | Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation |
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| المؤلفون: | Felts, Andrew S., Rodriguez, Alice L., Blobaum, Anna L., Morrison, Ryan D., Bates, Brittney S., Thompson Gray, Analisa, Rook, Jerri M., Tantawy, Mohammed N., Byers, Frank W., Chang, Sichen, Venable, Daryl F., Luscombe, Vincent B., Tamagnan, Gilles D., Niswender, Colleen M., Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Emmitte, Kyle A. |
| المساهمون: | William K. Warren Foundation, National Institute on Drug Abuse, National Institute of Mental Health, Seaside Therapeutics |
| المصدر: | Journal of Medicinal Chemistry ; volume 60, issue 12, page 5072-5085 ; ISSN 0022-2623 1520-4804 |
| بيانات النشر: | American Chemical Society (ACS) |
| سنة النشر: | 2017 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1021/acs.jmedchem.7b00410 |
| الاتاحة: | http://dx.doi.org/10.1021/acs.jmedchem.7b00410 http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00410 https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00410 |
| Rights: | http://pubs.acs.org/page/policy/authorchoice_termsofuse.html |
| رقم الانضمام: | edsbas.E0D160C8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acs.jmedchem.7b00410 |
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