Academic Journal
Pulmonary Liposarcoma of Probable Primary Origin in a Patient with Severe SARS-CoV-2 Pneumonia ; Liposarcoma pulmonar de probable origen primario en paciente con neumonía grave por SARS-CoV-2
| العنوان: | Pulmonary Liposarcoma of Probable Primary Origin in a Patient with Severe SARS-CoV-2 Pneumonia ; Liposarcoma pulmonar de probable origen primario en paciente con neumonía grave por SARS-CoV-2 |
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| المؤلفون: | Osses Vergara, Francisco, Melo Alarcón, Paulo, Vera Fuentes, Luis, Andino Sarmiento, Paulette |
| المصدر: | Respirar; Vol. 14 No. 2 (2022): June; 115-120 ; Respirar; Vol. 14 Núm. 2 (2022): Junio; 115-120 ; 2953-3414 |
| بيانات النشر: | Asociación Latinoamericana de Tórax (ALAT) |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | liposarcoma, liposarcoma pulmonar, neumonía grave, ventilación mecánica invasiva, fibrobroncoscopía, pulmonary liposarcoma, severe pneumonia, invasive mechanical ventilation, fiberoptic bronchoscopy |
| الوصف: | Liposarcoma is a malignant tumor derived from adipose tissue that represents up to 20% of all soft tissue sarcomas. It has a higher incidence in men, and between the 5th and 7th decade of life. Primary pulmonary origin is rare, being identified in less than 0.5% of all lung tumors. There are few cases of pulmonary liposarcoma reported in the literature. We present the case of a 57-year-old man, with a history of arterial hypertension, type-2 diabetes mellitus and alcoholic liver cirrhosis, hospitalized for severe SARS-CoV-2 pneumonia. Upon admission, chest CT revealed multiple diffuse, patchy ground-glass areas, with no organizing areas or evident endobronchial lesions. He evolved with deterioration in pulmonary mechanics and oxygenation, requiring connection to invasive mechanical ventilation. Control chest X-rays without evidence of condensation, atelectasis or pleural occupation. Fiberoptic bronchoscopy showed a round, whitish endobronchial mass towards the left posterior apical bronchus that oscillated with ventilation, and whose immunohistochemistry was positive for MDM2, CDK4, P16, S-100, and negative for PAN-CK, consistent with well-differentiated liposarcoma. Due to catastrophic ventilatory failure and subsequent death, it was not possible to expand the search for an extrapulmonary primary tumor. Fiberoptic bronchoscopy is crucial in critically ill patients who need invasive mechanical ventilation, in whom there is also no improvement in oxygenation or pulmonary mechanics despite established therapy. ; El liposarcoma es un tumor maligno derivado del tejido adiposo, que representa hasta un 20% del total de sarcomas de partes blandas. Tiene mayor incidencia en hombres, y entre la 5ª y 7ª década de vida. Es poco frecuente el origen primario pulmonar, identificándose en menos del 0.5% del total de tumores pulmonares. Existen pocos casos de liposarcoma pulmonar reportados en la literatura. Presentamos el caso de un hombre de 57 años, con antecedentes de hipertensión arterial, diabetes mellitus tipo 2 y ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Spanish; Castilian |
| Relation: | https://respirar.alatorax.org/index.php/respirar/article/view/103/59; https://respirar.alatorax.org/index.php/respirar/article/view/103 |
| DOI: | 10.55720/respirar.14.2.7 |
| الاتاحة: | https://respirar.alatorax.org/index.php/respirar/article/view/103 https://doi.org/10.55720/respirar.14.2.7 |
| Rights: | https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.E077C60D |
| قاعدة البيانات: | BASE |
| DOI: | 10.55720/respirar.14.2.7 |
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