Academic Journal
Cortisol as a Target for Treating Mental Disorders: A Promising Avenue for Therapy
| العنوان: | Cortisol as a Target for Treating Mental Disorders: A Promising Avenue for Therapy |
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| المؤلفون: | Patel, Vijay K, Vaishnaw, Aayush, Shirbhate, Ekta, Kore, Rakesh, Singh, Vaibhav, Veerasamy, Ravichandran, Rajak, Harish |
| المصدر: | Mini-Reviews in Medicinal Chemistry ; volume 24, issue 6, page 588-600 ; ISSN 1389-5575 |
| بيانات النشر: | Bentham Science Publishers Ltd. |
| سنة النشر: | 2024 |
| الوصف: | Cortisol, commonly known as the "stress hormone," plays a critical role in the body's response to stress. Elevated cortisol levels have been associated with various mental disorders, including anxiety, depression, and post-traumatic stress disorder. Consequently, researchers have explored cortisol modulation as a promising avenue for treating these conditions. However, the availability of research on cortisol as a therapeutic option for mental disorders is limited, and existing studies employ diverse methodologies and outcome measures. This review article aimed to provide insights into different treatment approaches, both pharmacological and non-pharmacological, which can effectively modulate cortisol levels. Pharmacological interventions involve the use of substances, such as somatostatin analogs, dopamine agonists, corticotropin-releasing hormone antagonists, and cortisol synthesis inhibitors. Additionally, non-pharmacological techniques, including cognitivebehavioral therapy, herbs and supplements, transcranial magnetic stimulation, lifestyle changes, and surgery, have been investigated to reduce cortisol levels. The emerging evidence suggests that cortisol modulation could be a promising treatment option for mental disorders. However, more research is needed to fully understand the effectiveness and safety of these therapies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.2174/0113895575262104230928042150 |
| الاتاحة: | http://dx.doi.org/10.2174/0113895575262104230928042150 https://www.eurekaselect.com/article/download?doi=10.2174/0113895575262104230928042150 https://www.eurekaselect.com/221961/article |
| رقم الانضمام: | edsbas.E050FE33 |
| قاعدة البيانات: | BASE |
| DOI: | 10.2174/0113895575262104230928042150 |
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