Academic Journal
Meta-analysis comparing percutaneous coronary intervention with coronary artery bypass grafting for non-ST elevation acute coronary syndrome in patients with multivessel or left main disease
العنوان: | Meta-analysis comparing percutaneous coronary intervention with coronary artery bypass grafting for non-ST elevation acute coronary syndrome in patients with multivessel or left main disease |
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المؤلفون: | Barssoum, Kirolos, Kumar, Ashish, Rai, Devesh, Kharsa, Adnan, Chowdhury, Medhat, Thakkar, Samarthkumar, Patel, Harsh P., Amin, Aqsa, Tan, Bryan, Ibrahim, Fadi, Bandyopadhyay, Dhrubjyoti, Elkaryoni, Ahmed, Elbadawi, Ayman, Abtahian, Farhad, Nanda, Navin C., Depta, Jeremiah |
المصدر: | Rochester Regional Health authored publications and proceedings |
بيانات النشر: | RocScholar |
سنة النشر: | 2022 |
مصطلحات موضوعية: | CABG, Left main coronary artery disease, MACE, Multivessel coronary disease, Non-ST-elevation acute coronary syndrome, Medicine and Health Sciences |
الوصف: | Outcomes of patients presenting with non-ST-elevation acute coronary syndrome (NSTE-ACS) with multivessel coronary disease (MVD) and/or unprotected left main coronary artery disease (CAD) revascularized with percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) is not well defined. MEDLINE/PubMed and EMBASE/Ovid were queried for studies that investigated PCI vs CABG in this disease subset. The primary outcome was major cardiac adverse events (MACE) at 30 days and long-term follow-up (3-5 years). The final analysis included 9 studies with a total of 9299 patients. No significant difference was observed between PCI and CABG in 30 days MACE (risk ratio [RR] 0.96; 95% confidence interval [CI] 0.38-2.39, all-cause mortality, myocardial infarction, and stroke. A meta-regression analysis revealed patients with a history of PCI had higher risk of MACE with PCI as compared with CABG. At long-term follow-up, PCI compared with CABG was associated with higher risk of MACE (RR 1.52; 95% CI 1.28-1.81), myocardial infarction, and repeat revascularization, while no difference was observed in the risk of stroke and all-cause mortality. In patients with NSTE-ACS and MVD or unprotected left main CAD, no differences were observed in the clinical outcomes between PCI and CABG at 30 days follow-up. With long-term follow-up, PCI was associated with a higher risk of MACE. |
نوع الوثيقة: | text |
اللغة: | unknown |
Relation: | https://scholar.rochesterregional.org/rrhpubs/1494; https://doi.org/10.1016/j.cpcardiol.2022.101306 |
DOI: | 10.1016/j.cpcardiol.2022.101306 |
الاتاحة: | https://scholar.rochesterregional.org/rrhpubs/1494 https://doi.org/10.1016/j.cpcardiol.2022.101306 |
رقم الانضمام: | edsbas.E031B177 |
قاعدة البيانات: | BASE |
DOI: | 10.1016/j.cpcardiol.2022.101306 |
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