التفاصيل البيبلوغرافية
| العنوان: |
In vitro evaluation of nanosecond electroporation against Trichophyton rubrum with or without antifungal drugs and terpenes |
| المؤلفون: |
Novickij, Vitalij, Švedienė, Jurgita, Paškevičius, Algimantas, Novickij, Jurij |
| المصدر: |
Mycoscience, Amsterdam : Elsevier B.V., 2017, Vol. 58, iss. 4, p. 261-266 ; ISSN 1340-3540 ; eISSN 1618-2545 |
| سنة النشر: |
2017 |
| المجموعة: |
LSRC VL (Lithuanian Social Research Centre Virtual Library) / LSTC VB (Lietuvos socialinių tyrimų centras virtualią biblioteką) |
| مصطلحات موضوعية: |
Dermatophytes, Electric field, Fungi, Inactivation, Pulsed power |
| الوصف: |
Increasing antimicrobial resistance among dermatophytes signals a need for development of new alternative therapeutic approaches for control of fungi. In this work, we analyse the antifungal activity of terpenes (linalool and y-terpene) and nanosecond electroporation. Square wave 100, 500 ns and 1 ms pulses have been evaluated in the study. Combinatorial treatments with antifungal drugs (terbinafine and itraconazole) and microsecond range (100 ms) electroporation were applied as references. We have determined that pulsed electric fields up to 30 kVcm 1 could be successfully used to inactivate T. rubrum both alone and in combination with antifungals. The applied nanosecond protocols reduced the survival of fungi up to 70%, while microsecond range protocols completely inactivated fungal colonies. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| Relation: |
http://vgtu.lvb.lt/VGTU:ELABAPDB22962397&prefLang=en_US |
| الاتاحة: |
http://vgtu.lvb.lt/VGTU:ELABAPDB22962397&prefLang=en_US |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.E01590A6 |
| قاعدة البيانات: |
BASE |