Academic Journal
Role of fetal magnetic resonance imaging in fetuses with congenital cytomegalovirus infection: multicenter study
| العنوان: | Role of fetal magnetic resonance imaging in fetuses with congenital cytomegalovirus infection: multicenter study |
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| المؤلفون: | Daniele Di Mascio, Giuseppe Rizzo, Asma Khalil, Antonella Giancotti, Lucia Manganaro, Silvia Visentin, Erich Cosmi, Federico Prefumo, Tamara Stampalija, Valentina D'Ambrosio, Roberto Brunelli, Marco Liberati, Danilo Buca, Barbara Matarrelli, Alice D'Amico, Ludovica Oronzii, Sara Tinari, Massimo Caulo, Luigia Gentile, Ilaria Fantasia, Ilenia Mappa, Giuseppe Maria Maruotti, Gabriele Saccone, Luigi Carbone, Laura Sarno, Gabriella Bracalente, Emma Bertucci, Filomena Giulia Sileo, Marcella Pellegrino, Marco De Santis, Antonio Lanzone, Lorenzo Pinelli, Flora Murru, Elena Trincia, Cristina Pajno, Sara Sorrenti, Lorenzo Vasciaveo, Luigi Nappi, Pantaleo Greco, Francesco D'Antonio |
| المساهمون: | Di Mascio Daniele, Rizzo Giuseppe, Khalil Asma, Giancotti Antonella, Manganaro Lucia, Visentin Silvia, Cosmi Erich, Prefumo Federico, Stampalija Tamara, D'Ambrosio Valentina, Brunelli Roberto, Liberati Marco, Buca Danilo, Matarrelli Barbara, D'Amico Alice, Oronzii Ludovica, Tinari Sara, Caulo Massimo, Gentile Luigia, Fantasia Ilaria, Mappa Ilenia, Maria Maruotti Giuseppe, Saccone Gabriele, Carbone Luigi, Sarno Laura, Bracalente Gabriella, Bertucci Emma, Giulia Sileo Filomena, Pellegrino Marcella, De Santis Marco, Lanzone Antonio, Pinelli Lorenzo, Murru Flora, Trincia Elena, Pajno Cristina, Sorrenti Sara, Vasciaveo Lorenzo, Nappi Luigi, Greco Pantaleo, D'Antonio Francesco |
| سنة النشر: | 2023 |
| المجموعة: | Università degli Studi di Brescia: OPENBS - Open Archive UniBS |
| مصطلحات موضوعية: | CMV, MRI, cytomegaloviru, hearing lo, infection, neurosonography, ultrasound |
| الوصف: | Objective: To investigate the role of fetal brain magnetic resonance imaging (MRI) in detecting associated anomalies in fetuses with congenital cytomegalovirus (CMV) infection and normal neurosonography. Methods: This was a multicenter, retrospective cohort study of patients examined between 2012 and 2021 in 11 referral fetal medicine centers in Italy. Inclusion criteria were fetuses with congenital CMV infection diagnosed by polymerase chain reaction analysis of amniotic fluid, pregnancies that underwent detailed multiplanar ultrasound assessment of the fetal brain as recommended by the International Society of Ultrasound in Obstetrics and Gynecology, maternal age ≥ 18 years, normal fetal karyotype and MRI performed within 3 weeks after the last ultrasound examination. The primary outcome was the rate of central nervous system (CNS) anomalies detected exclusively on MRI and confirmed after birth or autopsy in fetuses with a prenatal diagnosis of congenital CMV infection and normal neurosonography at diagnosis. Additional CNS anomalies were classified into anomalies of the ventricular and the periventricular zone, intracranial calcifications in the basal ganglia or germinal matrix, destructive encephalopathy in the white matter, malformations of cortical development, midline anomalies, posterior fossa anomalies and complex brain anomalies. We evaluated the relationship between the incidence of structural CNS malformations diagnosed exclusively on fetal MRI and a number of maternal and gestational characteristics. Univariate and multivariate logistic regression analyses were used to identify and adjust for potential independent predictors of the MRI diagnosis of fetal anomalies. Results: The analysis included 95 fetuses with a prenatal diagnosis of congenital CMV infection and normal neurosonography referred for prenatal MRI. The rate of structural anomalies detected exclusively at fetal MRI was 10.5% (10/95). When considering the type of anomaly, malformations of cortical development were detected on MRI in ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/36056700; info:eu-repo/semantics/altIdentifier/wos/WOS:000950613100008; volume:61; issue:1; firstpage:67; lastpage:73; numberofpages:7; journal:ULTRASOUND IN OBSTETRICS & GYNECOLOGY; https://hdl.handle.net/11379/568291; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85143275638 |
| DOI: | 10.1002/uog.26054 |
| الاتاحة: | https://hdl.handle.net/11379/568291 https://doi.org/10.1002/uog.26054 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.DFB8136C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/uog.26054 |
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