Academic Journal
Spontaneously Reported Adverse Drug Reactions and Their Description in Hospital Discharge Reports: A Retrospective Study
| العنوان: | Spontaneously Reported Adverse Drug Reactions and Their Description in Hospital Discharge Reports: A Retrospective Study |
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| المؤلفون: | Aguilera Martín, Cristina, Agustí Escasany, Maria Antònia, Pérez Esquirol, Eulàlia, Gracia Gozalo, Rosa Maria, Diogène Fadini, Eduard, Danes Carreras, Immaculada |
| المساهمون: | Institut Català de la Salut, Aguilera C, Agustí A, Diogène E, Danés I Servei de Farmacologia Clínica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Farmacologia, Terapèutica i Toxicologia, Universitat Autònoma de Barcelona, Bellaterra, Spain. Grup de Recerca en Malalties Immunomediades i Teràpies Innovadores, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Pérez E Servei de Farmacologia Clínica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Farmacologia, Terapèutica i Toxicologia, Universitat Autònoma de Barcelona, Bellaterra, Spain. Gracia RM Unitat de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus |
| المصدر: | Scientia |
| بيانات النشر: | MDPI |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Farmacologia clínica, Medicaments - Prescripció, Medicaments - Efectes secundaris, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Evaluation Studies as Topic::Product Surveillance, Postmarketing::Adverse Drug Reaction Reporting Systems, CHEMICALS AND DRUGS::Pharmaceutical Preparations::Prescription Drugs, DISCIPLINES AND OCCUPATIONS::Natural Science Disciplines::Biological Science Disciplines::Pharmacology::Pharmacology, Clinical, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::estudios de evaluación como asunto::vigilancia de productos comercializados::sistemas de información de reacciones adversas a medicamentos, VIGILANCIA SANITARIA::control sanitario de productos::control de medicamentos y estupefacientes::preparados farmacéuticos::medicamentos por prescripción, DISCIPLINAS Y OCUPACIONES::disciplinas de las ciencias naturales::disciplinas de las ciencias biológicas::farmacología::farmacología clínica |
| الوصف: | Reacció adversa al fàrmac; Informe d'alta hospitalària; Farmacovigilància ; Reacción adversa al medicamento; Informe de alta hospitalaria; Farmacovigilancia ; Adverse drug reaction; Hospital discharge report; Pharmacovigilance ; The inclusion of spontaneously reported adverse drug reactions (ADRs) in hospital discharge reports was examined, in addition to the factors associated with their inclusion, the resulting therapeutic decisions, and any recommendations made upon patient discharge regarding the suspected offending drugs. ADRs that were spontaneously reported during 2017 and 2018 to the pharmacovigilance program were retrospectively analyzed. Information regarding patient characteristics, drug treatments, and ADRs was collected from the ADR notifications and from patient electronic medical records. The dependent variable was the mentioning of ADRs in the discharge reports, while characteristics of the ADRs, pharmacovigilance causality algorithms, and some of the suspected drugs themselves were the independent variables during bivariant analysis. A total of 286 reports of suspected ADRs from 271 patients (50.2% female; 77% adults) were included. Information regarding the ADRs was present in the discharge reports for 238 reports (83.2%); the ADR seriousness and the lack of potential alternative causes were the only associated factors. Withdrawal or withdrawal and substitution by an alternative drug were the most common therapeutic decisions, although often no recommendation was made. Overall, there is still room for improvement in terms of including information related to ADRs in hospital discharge reports. ; This research received no external funding. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2077-0383 |
| Relation: | Journal of Clinical Medicine;10(15); https://doi.org/10.3390/jcm10153293; Aguilera C, Agustí A, Pérez E, Gracia RM, Diogène E, Danés I. Spontaneously Reported Adverse Drug Reactions and Their Description in Hospital Discharge Reports: A Retrospective Study. J Clin Med. 2021 Aug;10(15):3293.; https://hdl.handle.net/11351/7343; 000682062700001 |
| DOI: | 10.3390/jcm10153293 |
| الاتاحة: | https://hdl.handle.net/11351/7343 https://doi.org/10.3390/jcm10153293 |
| Rights: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.DF8A932 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20770383 |
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| DOI: | 10.3390/jcm10153293 |