Academic Journal
The NCBI Comparative Genome Viewer (CGV) is an interactive visualization tool for the analysis of whole-genome eukaryotic alignments.
العنوان: | The NCBI Comparative Genome Viewer (CGV) is an interactive visualization tool for the analysis of whole-genome eukaryotic alignments. |
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المؤلفون: | Sanjida H Rangwala, Dmitry V Rudnev, Victor V Ananiev, Dong-Ha Oh, Andrea Asztalos, Barrett Benica, Evgeny A Borodin, Nathan Bouk, Vladislav I Evgeniev, Vamsi K Kodali, Vadim Lotov, Eyal Mozes, Marina V Omelchenko, Sofya Savkina, Ekaterina Sukharnikov, Joël Virothaisakun, Terence D Murphy, Kim D Pruitt, Valerie A Schneider |
المصدر: | PLoS Biology, Vol 22, Iss 5, p e3002405 (2024) |
بيانات النشر: | Public Library of Science (PLoS) |
سنة النشر: | 2024 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | Biology (General), QH301-705.5 |
الوصف: | We report a new visualization tool for analysis of whole-genome assembly-assembly alignments, the Comparative Genome Viewer (CGV) (https://ncbi.nlm.nih.gov/genome/cgv/). CGV visualizes pairwise same-species and cross-species alignments provided by National Center for Biotechnology Information (NCBI) using assembly alignment algorithms developed by us and others. Researchers can examine large structural differences spanning chromosomes, such as inversions or translocations. Users can also navigate to regions of interest, where they can detect and analyze smaller-scale deletions and rearrangements within specific chromosome or gene regions. RefSeq or user-provided gene annotation is displayed where available. CGV currently provides approximately 800 alignments from over 350 animal, plant, and fungal species. CGV and related NCBI viewers are undergoing active development to further meet needs of the research community in comparative genome visualization. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 1544-9173 1545-7885 |
Relation: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002405&type=printable; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885; https://doaj.org/article/5f3ee861c1894e2e9be54c30e3c86d5c |
DOI: | 10.1371/journal.pbio.3002405 |
الاتاحة: | https://doi.org/10.1371/journal.pbio.3002405 https://doaj.org/article/5f3ee861c1894e2e9be54c30e3c86d5c |
رقم الانضمام: | edsbas.DF836E39 |
قاعدة البيانات: | BASE |
تدمد: | 15449173 15457885 |
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DOI: | 10.1371/journal.pbio.3002405 |