التفاصيل البيبلوغرافية
| العنوان: |
Phytochemical Characterization and Bioactivity of Asparagus acutifolius: A Focus on Antioxidant, Cytotoxic, Lipase Inhibitory and Antimicrobial Activities |
| المؤلفون: |
Amel Hamdi, Sara Jaramillo-Carmona, Rocío Rodríguez-Arcos, Ana Jiménez-Araujo, Mokhtar Lachaal, Najoua Karray-Bouraoui, Rafael Guillén-Bejarano |
| المصدر: |
Molecules; Volume 26; Issue 11; Pages: 3328 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2021 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Asparagus acutifolius, phytochemicals, antioxidant activity, lipase inhibitory activity, cytotoxicity, antimicrobial activity, LC-MS, HPLC-DAD, HPLC/Q-TOF-MS |
| جغرافية الموضوع: |
agris |
| الوصف: |
The phytochemical composition of leaves, stems, pericarps and rhizomes ethanolic extracts of Asparagus acutifolius were characterized by HPLC-DAD-MS. A. acutifolius samples contain at least eleven simple phenolics, one flavonon, two flavonols and six steroidal saponins. The stem extracts showed the highest total phenolic acid and flavonoid contents, where cafeic acid and rutin were the main compounds. No flavonoids were detected in the leaf, pericarp or rhizome while caffeic acid and ferulic acid were the predominant. Steroidal saponins were detected in the different plant parts of A. acutifolius, and the highest contents were found in the rhizome extracts. The stem extracts exhibited the highest antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) and the highest 2,2-azino-bis (3 ethylbenzothiazoline-6-sulphonic acid) (ABTS) scavenging activity was found in the pericarp extracts. The rhizome and leaf extracts showed a potent cytotoxic activity against HCT-116 and HepG2 cell lines. Moreover, the pericarp and rhizome extracts revealed a moderate lipase inhibitory activity. The leaf and rhizome extracts were screened for their antimicrobial activity against human pathogenic isolates. The leaf extract exhibited a powerful inhibitory activity against all the bacteria and fungi tested. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Natural Products Chemistry; https://dx.doi.org/10.3390/molecules26113328 |
| DOI: |
10.3390/molecules26113328 |
| الاتاحة: |
https://doi.org/10.3390/molecules26113328 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.DF7818D7 |
| قاعدة البيانات: |
BASE |