Academic Journal
Human spotted fever group Rickettsia seroprevalence and associated epidemiologic factors among diverse, marginalized populations in South Carolina
| العنوان: | Human spotted fever group Rickettsia seroprevalence and associated epidemiologic factors among diverse, marginalized populations in South Carolina |
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| المؤلفون: | Lídia Gual-Gonzalez, Stella C.W. Self, Madeleine Meyer, Omar Cantillo-Barraza, Myriam E. Torres, Melissa S. Nolan |
| المصدر: | Ticks and Tick-Borne Diseases, Vol 15, Iss 2, Pp 102288- (2024) |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2024 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Spotted fever group Rickettsia, Seroprevalence, Social determinants of health, Tick-borne diseases, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Illness caused by spotted fever group Rickettsia (SFGR) is increasing nationally, with affluent, white residents most likely to be diagnosed. The common under-representativeness of marginalized populations in research studies and these vulnerable populations’ health inequities make veritable epidemiologic risk factor profiling challenging, which inhibits equitable public health intervention. The current study leveraged 749 banked sera and associated surveys from a cross-sectional minority-represented COVID-19 study to perform an SFGR seroprevalence investigation. SFGR titers (1:64, 1:128, 1:256, 1:512, and 1:1024) were measured using commercially available indirect fluorescent antibody slides—SFGR positive cases were defined as titers ≥1:128. Multivariable logistic regression and Getis-Ord-Gi* hotspot analyses were used to identify seropositivity-associated factors and determine seropositive clusters. Among a mostly minority and lower socioeconomic population, a 3.4 % SFGR seropositivity was noted at the ≥1:128 titer level. Male gender (Odds Ratio (OR): 3.20; adjusted Odds Ratio (aOR)s: 3.73), age (aOR: 1.05), any frequency of tick bite (OR: 2.29), and spending time working outdoors (OR: 5.05) were associated with SFGR IgG seropositivity. Moreover, the geospatial analysis showed clusters of seropositivity in areas where previous case reports occurred, suggesting potential endemic foci. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1877-9603 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1877959X23001693; https://doaj.org/toc/1877-9603; https://doaj.org/article/509cb23aa2314b91a698dd9bc31ef544 |
| DOI: | 10.1016/j.ttbdis.2023.102288 |
| الاتاحة: | https://doi.org/10.1016/j.ttbdis.2023.102288 https://doaj.org/article/509cb23aa2314b91a698dd9bc31ef544 |
| رقم الانضمام: | edsbas.DED42557 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 18779603 |
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| DOI: | 10.1016/j.ttbdis.2023.102288 |