التفاصيل البيبلوغرافية
| العنوان: |
K i Values for Pentamidine Determined for Selected CNS targets together with the relative selectivity value when the K i is compared to trypanocidal activity (IC 50 ).These results, together with the calculated relative selectivity values compared with trypanocidal affinity, are listed in Table 3. |
| المؤلفون: |
Lisa Sanderson (3897346), Marcelo da Silva (2714077), Gayathri N. Sekhar (3897349), Rachel C. Brown (2652667), Hollie Burrell-Saward (488101), Mehmet Fidanboylu (343341), Bo Liu (127343), Lea Ann Dailey (1416529), Cécile A. Dreiss (2739985), Chris Lorenz (10654957), Mark Christie (3262812), Shanta J. Persaud (10654960), Vanessa Yardley (2179120), Simon L. Croft (10090913), Margarita Valero (1741714), Sarah A. Thomas (9983449) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Microbiology, Cell Biology, Neuroscience, Pharmacology, Biotechnology, Developmental Biology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, MIN, additive trypanocidal effect, stage 2 HAT, BBB drug penetration, diseases inititative recommendations, increases CNS exposure, target candidate profile, insulin secretion, dose brain penetration study, NANOHAT, Principal Findings Screening pentam., pentamidine CNS delivery, 40 CNS targets, imidazoline 2 receptor, formulation, sickness drug Background Human, parasite Trypanosoma brucei sspp |
| الوصف: |
K i Values for Pentamidine Determined for Selected CNS targets together with the relative selectivity value when the K i is compared to trypanocidal activity (IC 50 ).These results, together with the calculated relative selectivity values compared with trypanocidal affinity, are listed in Table 3 . |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/dataset/K_sub_i_sub_Values_for_Pentamidine_Determined_for_Selected_CNS_targets_together_with_the_relative_selectivity_value_when_the_K_sub_i_sub_is_compared_to_trypanocidal_activity_IC_sub_50_sub_These_results_together_with_the_calculated_relative_/14427643 |
| DOI: |
10.1371/journal.pntd.0009276.t003 |
| الاتاحة: |
https://doi.org/10.1371/journal.pntd.0009276.t003 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.DD316796 |
| قاعدة البيانات: |
BASE |