التفاصيل البيبلوغرافية
| العنوان: |
Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons |
| المؤلفون: |
R. L. Morris, P. J. Hollenbeck |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d1/3e/J_Cell_Biol_1995_Dec_1_131(5)_1315-1326.tar.gz |
| سنة النشر: |
1995 |
| المجموعة: |
CiteSeerX |
| الوصف: |
A large body of evidence indicates that microtubules (MTs) conduct organelle transport in axons, but recent studies on extruded squid axoplasm have suggested that actin microfilaments (MFs) may also play a role in this process. To investigate the separate contributions to transport of each class of cytoskeletal element in intact vertebrate axons, we have monitored mitochondrial movements in chick sympathetic neurons experimentally manipulated to eliminate MTs, MFs, or both. First, we grew neurons in the continuous presence of: (a) cytochalasin E to create neurites which had never contained MFs; or (b) nocodazole or vinblastine to produce neurites which had never contained MTs. Mitochondria moved bidirecfionally at normal velocities along the length of neurites which contained |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/zip |
| اللغة: |
English |
| Relation: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.273.1663 |
| الاتاحة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.273.1663 |
| Rights: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.DD304E50 |
| قاعدة البيانات: |
BASE |