Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria

التفاصيل البيبلوغرافية
العنوان: Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria
المؤلفون: DIKKO, M, BELLO, SO, CHIKA, A, MUNGADI, IA, SARKINGOBIR, Y, UMAR, AI
المصدر: Journal of Applied Sciences and Environmental Management (ISSN: 1119-8362) Vol 24 Num 4
بيانات النشر: World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt
سنة النشر: 2021
المجموعة: Bioline International (Reference Center on Environmental Information, Brazil)
مصطلحات موضوعية: Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance
جغرافية الموضوع: Origin of publication: Nigeria
الوصف: The objective of this paper was to determine the effect of tamsulosin use on plasma insulin status in benign prostatic hyperplasia (BPH) patients in Sokoto, Nigeria. Standard methods and procedures were used. At 2nd and 3rd months of tamsulosin use, there was a significant increase (P<0.05) in plasma insulin values compared to baseline. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was revealed compared to baseline and 2nd month values. Other inter-mean values comparisons were not significantly different (P>0.05). Plasma insulin at 4th months of the study in BPH patients (45-54 years) treated with tamsulosin revealed a significant increase (P<0.05) compared to baseline values. Other inter-mean values comparisons were not significantly different (P>0.05). BPH patients (aged 55-64 years) at 3rd month showed a significant increase (P<0.05) in plasma insulin values compared to baseline values. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was seen compared to baseline and 1st month values. Other inter-mean values comparisons were not significantly different (P>0.05). In BPH patients aged 65 and above, there was no significant difference (P>0.05) in plasma insulin values from 1st through 4th month compared to baseline and other inter mean values comparisons. Plasma insulin at 0th , 1st , 2nd , 3rd and 4th months of BPH patients of different age groups treated with tamsulosin revealed no significant differences (P>0.05). This study revealed that tamsulosin use in the patients lead to significant increase in plasma insulin level (hyperinsulinemia). Careful and routine monitoring of BPH patients should be done. Patients need enough exercise activities and some drugs can be administered to alleviate elevated glucose or insulin.
نوع الوثيقة: other/unknown material
وصف الملف: html
اللغة: English
Relation: http://www.bioline.org.br/ja; http://www.bioline.org.br/abstract?id=ja20078
الاتاحة: http://www.bioline.org.br/abstract?id=ja20078
Rights: Copyright 2020 - Dikko et al.
رقم الانضمام: edsbas.DCCC4F13
قاعدة البيانات: BASE