Academic Journal
高血压与年龄增长叠加对左心房大小与功能的影响 ; Synergistic effect of hypertension and aging on left atrial volume and function
| العنوان: | 高血压与年龄增长叠加对左心房大小与功能的影响 ; Synergistic effect of hypertension and aging on left atrial volume and function |
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| المؤلفون: | 杨颖, 张宝娓, 齐丽彤, 马为, 孟磊, 霍勇 |
| المساهمون: | 100034,北京大学第一医院心内科 |
| المصدر: | 万方 ; PubMed ; http://d.g.wanfangdata.com.cn/Periodical_zhnk201408009.aspx |
| بيانات النشر: | 中华内科杂志 |
| سنة النشر: | 2014 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | 高血压 心房功能,左 年龄因素 超声心动描记术 Hypertension Atrial function,left Age factors Echocardiography |
| الوصف: | 目的 评价高血压与年龄增长叠加对左心房大小与功能的影响.方法 使用738例社区心血管疾病高危人群横断面资料,按年龄分组(41～ 59岁、60 ～ 69岁、≥70岁)并划分高血压与非高血压亚组.测量左心房容积指数,并使用二维斑点追踪超声心动图技术测量舒张晚期(心房收缩期)左心房应变(Sa)、舒张早期应变(Se)、总应变(Stot=Sa+Se),及舒张晚期应变率(SRa)、收缩期应变率(SRs)、舒张早期应变率(SRe),比较各组上述指标.结果 左心房容积指数非高血压组各年龄段差异无统计学意义,高血压组随年龄增长而增大;左心房通道功能指标(Se、SRe)两组均随年龄增长降低,但各年龄组高血压组均显著低于非高血压组,测值在41～59岁高血压组与60 ～ 69岁非高血压组接近[Se:(11.0±4.4)％比(11.6±4.7)％,SRe:(1.0±0.4)s-1比(1.0±0.3)s-1]、高血压60 ～ 69岁组与非高血压≥70岁组接近[Se:(10.1±4.0)％比(9.5±5.4)％,SRe:(0.9 ±0.3)s-1比(0.8±0.4)s-].左心房储存功能指标(Stot、SRs)、收缩功能指标(Sa、SRa)高血压组随年龄增长而降低,非高血压组无显著变化.结论 单纯年龄增长不导致左心房扩大,高血压与年龄增长叠加造成左心房扩大.高血压加速年龄增长所致左心房时相功能障碍. ; To assess the effect of combined hypertension (HT) and aging on left atrial (LA) size and phasic function.This evaluation was based on the data from a cross-sectional study including 738 subjects with high risk for cardiovascular disease from an urban community in Beijing. Subjects were divided into 3 groups according to age (41-59, 60-69 and ≥ 70 years) and further into HT and non-HT sub-groups. LA volume index were calculated and LA global longitudinal strain in late diastole (Sa), early diastole (Se), and total strain (Stot = Sa+ Se), and strain rate in late diastole (SRa), systole (SRs), and early diastole (SRe) were measured using off-line speckle-tracking echocardiography.LA volume index increased significantly in HT groups with aging, whereas no changes could be viewed in non-HT subjects among all age groups. LA conduit index (Se and SRe) decreased with aging in both HT and non-HT subjects with more sever in HT subjects than in non-HT subjects in all age groups. The LA conduit index in 41-59 year-HT, and in 60-69 year-HT subjects were comparable with that in 60-69 year-non-HT subjects [Se (11.0 ± 4.4)% vs (11.6 ± 4.7)%, SRe (1.0 ± 0.4) s(-1) vs (1.0 ± 0.3) s(-1)], and in ≥ 70 year-non-HT subjects [Se(10.1 ± 4.0)% vs (9.5 ± 5.4)%, SRe (0.9 ± 0.3)s(-1) vs (0.8 ± 0.4) s(-1)], respectively. LA reservoir (Stot and SRs) and contraction (Sa and SRa) index also decreased with aging in HT but not in non-HT subjects.Aging along ... |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | Chinese |
| تدمد: | 0578-1426 |
| Relation: | 中华内科杂志.2014,53,(8),617-621.; 650901; http://hdl.handle.net/20.500.11897/188552 |
| DOI: | 10.3760/cma.j.issn.0578-1426.2014.08.009 |
| الاتاحة: | https://hdl.handle.net/20.500.11897/188552 https://doi.org/10.3760/cma.j.issn.0578-1426.2014.08.009 |
| رقم الانضمام: | edsbas.DCCAE5F4 |
| قاعدة البيانات: | BASE |
| تدمد: | 05781426 |
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| DOI: | 10.3760/cma.j.issn.0578-1426.2014.08.009 |