Academic Journal
Highthroughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable resistance
| العنوان: | Highthroughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable resistance |
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| المؤلفون: | Bart, R., Cohn, M., Kassen, A., McCallum, E., Shybut, M., Petriello, A., Krasileva, K., Dahlbeck, D., Medina, C., Alicai, Titus, Kumar, P. Lava, Moreira, L., Neto, J., Verdier, Valerie M., Santana, M., Kositcharoenkul, N., Vanderschuren, H., Gruissem, W., Bernal, A., Staskawicz, B. |
| المصدر: | Proceedings of the National Academy of Sciences of the United States of America |
| بيانات النشر: | Proceedings of the National Academy of Sciences |
| سنة النشر: | 2017 |
| المجموعة: | CGIAR CGSpace (Consultative Group on International Agricultural Research) |
| مصطلحات موضوعية: | innate immunity, type three effectors, next-generation sequencing, cassava, plant diseases, xanthomonas axonopodis |
| الوصف: | Cassava bacterial blight (CBB), incited by Xanthomonas axonopodis pv. manihotis (Xam), is the most important bacterial disease of cassava, a staple food source for millions of people in developing countries. Here we present a widely applicable strategy for elucidating the virulence components of a pathogen population. We report Illumina-based draft genomes for 65 Xam strains and deduce the phylogenetic relatedness of Xam across the areas where cassava is grown. Using an extensive database of effector proteins from animal and plant pathogens, we identify the effector repertoire for each sequenced strain and use a comparative sequence analysis to deduce the least polymorphic of the conserved effectors. These highly conserved effectors have been maintained over 11 countries, three continents, and 70 y of evolution and as such represent ideal targets for developing resistance strategies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0027-8424 |
| Relation: | Bart, R., Cohn, M., Kassen, A., McCallum, E., Shybut, M., Petriello, A., … Staskawicz, B. (2012). Highthroughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable. Resistance. In: Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1972-E1979.; https://hdl.handle.net/10568/79848; https://doi.org/10.1073/pnas.1208003109 |
| DOI: | 10.1073/pnas.1208003109 |
| الاتاحة: | https://hdl.handle.net/10568/79848 https://doi.org/10.1073/pnas.1208003109 |
| Rights: | Open Access |
| رقم الانضمام: | edsbas.DC24A0AA |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00278424 |
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| DOI: | 10.1073/pnas.1208003109 |