Academic Journal
Exploring Modular Glycolipids Involved in Nematode Chemical Communication
| العنوان: | Exploring Modular Glycolipids Involved in Nematode Chemical Communication |
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| المؤلفون: | von Reuss, Stephan H. |
| المصدر: | CHIMIA; Bd. 72 Nr. 5 (2018): News from New Chemistry Professors in Switzerland; 297 ; CHIMIA; Vol. 72 No. 5 (2018): News from New Chemistry Professors in Switzerland; 297 ; 2673-2424 ; 0009-4293 |
| بيانات النشر: | Swiss Chemical Society |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Ascarosides, Chemical ecology, Glycolipids, Modular metabolites, Nematodes |
| الوصف: | Chemical communication in nematodes has been known for over half a century, but the underlying molecular basis remained largely elusive. Recent advances in analytical techniques facilitated the characterization of a modular glycolipid library based on the dideoxysugar L-ascarylose, which modulates behavior and development in the model organism C. elegans. Ascaroside signaling is highly conserved in nematodes and represents a key factor in nematode chemical ecology. Ascaroside biosynthesis depends on the co-option of the peroxisomal ?-oxidation cycle and in addition integrates a large diversity of additional building blocks derived from various primary metabolic pathways to give rise to species-specific modular assemblies, thus, transcending the concept of strictly segregated primary versus secondary metabolism. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://www.chimia.ch/chimia/article/view/2018_297/749; https://www.chimia.ch/chimia/article/view/2018_297 |
| DOI: | 10.2533/chimia.2018.297 |
| الاتاحة: | https://www.chimia.ch/chimia/article/view/2018_297 https://doi.org/10.2533/chimia.2018.297 |
| Rights: | Copyright (c) 2018 Swiss Chemical Society ; https://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.DBB430C8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.2533/chimia.2018.297 |
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