Academic Journal
Advance Access Publication
| العنوان: | Advance Access Publication |
|---|---|
| المؤلفون: | Ryoichi Shin, Momoyo Suzuki, Takeo Mizutani, Nobuyuki Susa |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://downloads.hindawi.com/journals/ecam/2009/165092.pdf. |
| المجموعة: | CiteSeerX |
| الوصف: | The effects of lactic acid bacteria-fermented soybean extract (Biofermentics TM ; BF) on experimental models of hepatic and renal disorders were investigated in vivo and in vitro. In rat, hepatitis induced by feeding of deoxycholic acid (DCA, 0.5 wt/wt, n = 6) or intraperitoneal injection of D-galactosamine (GMN, 500 mg/body wt, n = 6), the increase in serum AST (aspartate aminotransferase) and ALT (alanine aminotransferase) levels were inhibited significantly (P < 0.05) by feeding a diet containing 5% dried BF. Moreover, the BF-administered rat group showed lower concentrations of blood urea nitrogen and a larger amount of urine as compared with values in the control group. Pretreatment of primary cell cultures of rat hepatic and renal cells with BF prior to exposure to dichromate (K 2 Cr 2 O 7 ) resulted in a marked decrease of dichromate-induced cytotoxicity as evaluated by the leakage of lactate dehydrogenase The levels of dichromate-induced lipid peroxidation, as monitored by malondialdehyde formation, were also reduced by pretreatment of hepatocytes with BF. These results suggest that BF may play a role in hepatic and renal disorders, and may be useful for maintaining health in humans as well. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.958; http://downloads.hindawi.com/journals/ecam/2009/165092.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1083.958 http://downloads.hindawi.com/journals/ecam/2009/165092.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.DB765E72 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |