Academic Journal
Method for Microfluidic Whole-Chip Temperature Measurement Using Thin-Film Poly(dimethylsiloxane)/Rhodamine B
| العنوان: | Method for Microfluidic Whole-Chip Temperature Measurement Using Thin-Film Poly(dimethylsiloxane)/Rhodamine B |
|---|---|
| المؤلفون: | Y Xia, G M Whitesides, J R Anderson, J M K Ng, I Gitlin, A D Stroock, J C Mcdonald, X Chen, H Wu, C Mao, T W Odom, V R Thalladi, J C Love, M U Kopp, A J Mello, A Manz, K J Slais, X H Chromatogr, Fang, M Adams, Pawliszyn, T Huang, J Pawliszyn, D Ross, L E Locascio, S M Kim, G J Sommer, M A Burns, E F Hasselbrink, J Khandurina, T E Mcknight, S C Jacobson, L C Waters, R S Foote, J M Ramsey, E T Lagally, I Medintz, R A Mathies, M E Lacey, A G Webb, J V Sweedler, M Gaitan |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://www.eng.uwaterloo.ca/%7Etglawdel/downloads/Papers/Samy_Glawdel_Ren_AC_08.pdf. |
| المجموعة: | CiteSeerX |
| الوصف: | A novel method is presented for on-chip temperature measurements using a poly(dimethylsiloxane) (PDMS) thin film dissolved with Rhodamine B dye. This thin film is sandwiched between two glass substrates (one of which is 150 µm thick) and bonded to a microchannel molded in a PDMS substrate. Whole-chip (liquid and substrate) temperature measurements can be obtained via fluorescent intensity visualization. For verification purposes, the thin film was tested with a tapered microchannel subjected to Joule heating, with resulting axial temperature gradients comparing well with numerical simulations. Errors induced by the definite film thickness are discussed and accounted for during experimental and analytical analysis. Alternative validation using the traditional in-channel Rhodamine B injection method was also attempted. The thin film has several advantages over traditional methods. First, false intensity readings due to adsorption and absorption of Rhodamine B into PDMS channels are eliminated. Second, whole-chip temperature measurements are possible. Third, separation of working liquid from Rhodamine B dye prevents possible electrophoresis effects. Recent developments in microfluidic and lab-on-a-chip devices has drawn ever-increasing attention from industrial and academic communities due to their far-reaching applications in chemical, biomedical, environmental, and food processing technologies. Such miniaturized devices generally consist of a glass or plastic microfluidic platform with integrated sample processing units such as mixers, dispensers, reactors, separators, and detection systems for performing chemical and biological assays. Advantages of microfluidic devices over traditional methods include reduced sample and reagent use, increased parallel processing capabilities, and portability. In recent times, there has been a general shift to polymer-based materials such as poly(dimethylsiloxane) (PDMS), due to rapid and low-cost fabrication via soft lithography techniques compared to traditional glass-based ... |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1060.5688; http://www.eng.uwaterloo.ca/%7Etglawdel/downloads/Papers/Samy_Glawdel_Ren_AC_08.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1060.5688 http://www.eng.uwaterloo.ca/%7Etglawdel/downloads/Papers/Samy_Glawdel_Ren_AC_08.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.DAEB394F |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |