Academic Journal
Differential diagnosis of adnexal masses: sequential use of the risk of malignancy index and HistoScanning, a novel computer‐aided diagnostic tool
| العنوان: | Differential diagnosis of adnexal masses: sequential use of the risk of malignancy index and HistoScanning, a novel computer‐aided diagnostic tool |
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| المؤلفون: | Vaes, E., Manchanda, R., Autier, P., Nir, R., Nir, D., Bleiberg, H., Robert, A., Menon, U. |
| المصدر: | Ultrasound in Obstetrics & Gynecology ; volume 39, issue 1, page 91-98 ; ISSN 0960-7692 1469-0705 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2011 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Objective To assess the value of ovarian Histo‐Scanning ™ , a novel computerized technique for interpreting ultrasound data, in combination with the risk of malignancy index (RMI) in improving triage for women with adnexal masses. Methods RMI indices were assessed in 199 women enrolled in a prospective study to investigate the use of HistoScanning. Ultrasound scores were obtained by blinded analysis of archived images. The following sequential test was developed: HistoScanning was modeled as a second‐line test for RMI between a lower cut‐off and an upper cut‐off. The optimal combination of these cut‐offs that together maximized the Youden index (Sensitivity + Specificity − 1) was determined. Results Using RMI at the standard cut‐off value of 250 resulted in a sensitivity of 74% and a specificity of 86%. When RMI was combined with HistoScanning, the highest accuracy was achieved by using HistoScanning as a sequential second‐line test for patients with RMI values between 105 and 2100. At these cut‐off values, sequential use of RMI and HistoScanning resulted in mean sensitivity and specificity estimates of 88% and 95%, respectively. Conclusions Our data suggest that HistoScanning may have the potential to improve the diagnostic accuracy of RMI, which could result in better triage for women with adnexal masses. Further prospective validation is warranted. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/uog.9079 |
| الاتاحة: | http://dx.doi.org/10.1002/uog.9079 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fuog.9079 https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1002/uog.9079 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.DAAF5BC3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/uog.9079 |
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