Academic Journal

Normal subcellular distribution of dynein-dynactin complex subunits and disturbances in neurodegenerative disease

التفاصيل البيبلوغرافية
العنوان: Normal subcellular distribution of dynein-dynactin complex subunits and disturbances in neurodegenerative disease
المؤلفون: D D Ateh, I Hussain, A Mustafa, K M Price, C D Nickols, M M Bird, L Greensmith, G Schiavo, Majid Hafezparast, E M C Fisher, C S Baker, J E Martin
سنة النشر: 2006
المجموعة: University of Sussex (US): Figshare
مصطلحات موضوعية: Uncategorised value
الوصف: Dynein and its co-factor dynactin form a complex which drives the retrograde transport of material in neurons necessary for their survival and proper functioning. For instance, over-expression of the dynamitin subunit or mutations within individual dynein-dynactin subunits have been found to cause motor neuron degeneration. The CNS distribution of the dynein dynactin complex was examined in order to test the hypothesis that this may be altered in neurodegenerative diseases.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
Relation: 10779/uos.23352839.v1; https://figshare.com/articles/journal_contribution/Normal_subcellular_distribution_of_dynein-dynactin_complex_subunits_and_disturbances_in_neurodegenerative_disease/23352839
الاتاحة: https://figshare.com/articles/journal_contribution/Normal_subcellular_distribution_of_dynein-dynactin_complex_subunits_and_disturbances_in_neurodegenerative_disease/23352839
Rights: Copyright not evaluated
رقم الانضمام: edsbas.DA1ACF8B
قاعدة البيانات: BASE