Academic Journal
Oxidative CH Bond Functionalization and Ring Expansion with TMSCHN 2 : A Copper(I)‐Catalyzed Approach to Dibenzoxepines and Dibenzoazepines
| العنوان: | Oxidative CH Bond Functionalization and Ring Expansion with TMSCHN 2 : A Copper(I)‐Catalyzed Approach to Dibenzoxepines and Dibenzoazepines |
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| المؤلفون: | Stopka, Tobias, Marzo, Leyre, Zurro, Mercedes, Janich, Simon, Würthwein, Ernst‐Ulrich, Daniliuc, Constantin G., Alemán, José, Mancheño, Olga García |
| المصدر: | Angewandte Chemie International Edition ; volume 54, issue 17, page 5049-5053 ; ISSN 1433-7851 1521-3773 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2015 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Tricyclic dibenzoxepines and dibenzazepines are important therapeutic agents for the pharmaceutical industry and academic research. However, their syntheses are generally rather tedious, requiring several steps that involve a Wagner–Meerwein‐type rearrangement under harsh conditions. Herein, we present the first copper(I)‐catalyzed oxidative CH bond functionalization and ring expansion with TMSCHN 2 to yield these important derivatives in a facile and straightforward way. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/anie.201411726 |
| الاتاحة: | http://dx.doi.org/10.1002/anie.201411726 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.201411726 https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201411726 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.D8C6214C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/anie.201411726 |
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