Academic Journal
Thrombosis Occurrence in COVID-19 Compared With Other Infectious Causes of ARDS: A Contemporary Cohort
| العنوان: | Thrombosis Occurrence in COVID-19 Compared With Other Infectious Causes of ARDS: A Contemporary Cohort |
|---|---|
| المؤلفون: | Coy-Canguçu, Andréa, Locachevic, Gisele A., Mariolano, João Carlos S., Soares, Kaio Henrique De O., Oliveira, José Diogo, Vaz, Camila De Oliveira, Vieira-Damiani, Gislaine, Mazetto, Bruna, Annichino-Bizzacchi, Joyce Maria, De Paula, Erich V., Orsi, Fernanda A. |
| المساهمون: | Fundação de Amparo à Pesquisa do Estado de São Paulo |
| المصدر: | Clinical and Applied Thrombosis/Hemostasis ; volume 29 ; ISSN 1076-0296 1938-2723 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2023 |
| الوصف: | Thrombosis occurrence in coronavirus disease 2019 (COVID-19) has been mostly compared to historical cohorts of patients with other respiratory infections. We retrospectively evaluated the thrombotic events that occurred in a contemporary cohort of patients hospitalized between March and July 2020 for acute respiratory distress syndrome (ARDS) according to the Berlin Definition and compared those with positive and negative real-time polymerase chain reaction results for wild-type severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) using descriptive analysis. The association between COVID-19 and thrombotic risk was evaluated using logistic regression. 264 COVID-19-positive (56.8% male, 59.0 years [IQR 48.6-69.7], Padua score on admission 3.0 [2.0-3.0]) and 88 COVID-19-negative patients (58.0% male, 63.7 years [51.2-73.5], Padua score 3.0 [2.0-5.0]) were included. 10.2% of non-COVID-19 and 8.7% of COVID-19 patients presented ≥ 1 clinically relevant thrombotic event confirmed by imaging exam. After adjustment for sex, Padua score, intensive care unit stay, thromboprophylaxis, and hospitalization length, the odds ratio for thrombosis in COVID-19 was 0.69 (95% CI, 0.30-1.64). We, therefore, conclude that infection-induced ARDS carries an inherent thrombotic risk, which was comparable between patients with COVID-19 and other respiratory infections in our contemporary cohort. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1177/10760296231175656 |
| الاتاحة: | https://doi.org/10.1177/10760296231175656 https://journals.sagepub.com/doi/pdf/10.1177/10760296231175656 https://journals.sagepub.com/doi/full-xml/10.1177/10760296231175656 |
| Rights: | https://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.D74AD65F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/10760296231175656 |
|---|