Academic Journal
Unravelling the Roles of Bacterial Nanomachines Bistability in Pathogens’ Life Cycle
| العنوان: | Unravelling the Roles of Bacterial Nanomachines Bistability in Pathogens’ Life Cycle |
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| المؤلفون: | Gory, Romain, Personnic, Nicolas, Blaha, Didier |
| المساهمون: | Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | ISSN: 2076-2607 ; Microorganisms ; https://hal.science/hal-04733157 ; Microorganisms, 2024, 12 (9), pp.1930. ⟨10.3390/microorganisms12091930⟩. |
| بيانات النشر: | HAL CCSD MDPI |
| سنة النشر: | 2024 |
| المجموعة: | Université Jean Monnet – Saint-Etienne: HAL |
| مصطلحات موضوعية: | bet-hedging, division of labor, nanomachines, type III secretion system, flagellum, phenotypic heterogeneity, community behavior, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology |
| الوصف: | International audience ; Bacterial nanomachines represent remarkable feats of evolutionary engineering, showcasing intricate molecular mechanisms that enable bacteria to perform a diverse array of functions essential to persist, thrive, and evolve within ecological and pathological niches. Injectosomes and bacterial flagella represent two categories of bacterial nanomachines that have been particularly well studied both at the molecular and functional levels. Among the diverse functionalities of these nanomachines, bistability emerges as a fascinating phenomenon, underscoring their dynamic and complex regulation as well as their contribution to shaping the bacterial community behavior during the infection process. In this review, we examine two closely related bacterial nanomachines, the type 3 secretion system, and the flagellum, to explore how the bistability of molecular-scale devices shapes the bacterial eco-pathological life cycle. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.3390/microorganisms12091930 |
| الاتاحة: | https://hal.science/hal-04733157 https://hal.science/hal-04733157v1/document https://hal.science/hal-04733157v1/file/microorganisms-12-01930-v2%20%281%29.pdf https://doi.org/10.3390/microorganisms12091930 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.D72D0B5A |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/microorganisms12091930 |
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