Academic Journal
Evaluating the sum of eye and motor components of the glasgow coma score as a predictor of extubation failure in patients with acute brain injury
| العنوان: | Evaluating the sum of eye and motor components of the glasgow coma score as a predictor of extubation failure in patients with acute brain injury |
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| المؤلفون: | Taran S., Perrot B., Angriman F., Cinotti R., Abback P. -S., Codorniu A., Citerio G., Ludovica Sala V., Astuto M., Tringali E., Alampi D., Rocco M., Giuseppina Maugeri J., Bellissima A., Filippini M., Lazzeri N., Cortegiani A., Ippolito M., Robba C., Battaglini D., Biston P., Fathi Al-Gharyani M., Chabanne R., Astier L., Soyer B., Gaugain S., Zimmerli A., Pietsch U., Filipovic M., Brandi G., Bicciato G., Serrano A., Monleon B., Van Vliet P., Marcel Gerretsen B., Xochitl Ortiz-Macias I., Oto J., Enomoto N., Matsuda T., Masui N., Garcon P., Zarka J., Vermeijden W. J., Daniel Cornet A., Reyes Inurrigarro S., Cirino Lara Dominguez R., Mercedes Bellini M., Milagros Gomez Haedo M., Lamot L., Orquera J., Biais M., Georges D., Baronia A., Carlos Miranda-Ackerman R., Jose Barbosa-Camacho F., Porter J., Lopez-Morales M., Geeraerts T., Compagnon B., Perez-Torres D., Prol-Silva E., Basheer Yahya H., Khaled A., Ghula M., Neville Andrea C., Maria Daniela P., Deana C., Vetrugno L., Rivera Chavez M. J., Mendoza Trujillo R., Legros V., Brochet B., Huet O., Geslain M., Van Der Jagt M., Van Steenkiste J., Ahmed H., Edward Coombs A., Welbourne J., Velarde Pineda A. A., Nubert Castillo V. H., Azab M. A., Azzam A. Y., Paul Van Meenen D. M., Adrian Gasca G., Arellano A., Galicia-Espinosa F., Carlos Garcia-Ramos J., Yadav G., Kumar Jha A., Robert-Edan V., Rodie-Talbere P. -A., Jain G., Panda S., Agarwal S., Deewan Y., Tariq Reza S., Hossain M. M., Papadas C., Chantziara V., Sklavou C., Hourmant Y., Grillot N., Pirracchio R., Akkari A., Abdelaty M., Hashim A., Launey Y., Masseret E., Lasocki S., Gergaud S., Mouclier N., Saxena S., Agrawal A., Bedanta Mishra S., Samal S., Cesar Mijangos J., Haenggi M., Gurjar M., Schultz M. J., Kaye C., Agustin Godoy D., Alvarez P., Ioakeimidou A., Ueno Y., Badenes R., Suei Elbuzidi A. A., Piagnerelli M., Elhadi M., Atef Azab M., Catherine Digitale J., Fong N., Campos Cerda R., De La Torre Peredo N., David Stevens R. |
| المساهمون: | Taran, S., Perrot, B., Angriman, F., Cinotti, R., Abback, P. -S., Codorniu, A., Citerio, G., Ludovica Sala, V., Astuto, M., Tringali, E., Alampi, D., Rocco, M., Giuseppina Maugeri, J., Bellissima, A., Filippini, M., Lazzeri, N., Cortegiani, A., Ippolito, M., Robba, C., Battaglini, D., Biston, P., Fathi Al-Gharyani, M., Chabanne, R., Astier, L., Soyer, B., Gaugain, S., Zimmerli, A., Pietsch, U., Filipovic, M., Brandi, G., Bicciato, G., Serrano, A., Monleon, B., Van Vliet, P., Marcel Gerretsen, B., Xochitl Ortiz-Macias, I., Oto, J., Enomoto, N., Matsuda, T., Masui, N., Garcon, P., Zarka, J., Vermeijden, W. J., Daniel Cornet, A., Reyes Inurrigarro, S., Cirino Lara Dominguez, R., Mercedes Bellini, M., Milagros Gomez Haedo, M., Lamot, L., Orquera, J., Biais, M., Georges, D., Baronia, A., Carlos Miranda-Ackerman, R., Jose Barbosa-Camacho, F., Porter, J., Lopez-Morales, M., Geeraerts, T., Compagnon, B., Perez-Torres, D., Prol-Silva, E., Basheer Yahya, H., Khaled, A., Ghula, M., Neville Andrea, C., Maria Daniela, P., Deana, C., Vetrugno, L., Rivera Chavez, M. J., Mendoza Trujillo, R., Legros, V., Brochet, B., Huet, O., Geslain, M., Van Der Jagt, M., Van Steenkiste, J., Ahmed, H., Edward Coombs, A., Welbourne, J., Velarde Pineda, A. A., Nubert Castillo, V. H., Azab, M. A., Azzam, A. Y., Paul Van Meenen, D. M., Adrian Gasca, G., Arellano, A., Galicia-Espinosa, F., Carlos Garcia-Ramos, J., Yadav, G., Kumar Jha, A., Robert-Edan, V., Rodie-Talbere, P. -A., Jain, G., Panda, S., Agarwal, S., Deewan, Y., Tariq Reza, S., Hossain, M. M. |
| بيانات النشر: | LIPPINCOTT WILLIAMS & WILKINS TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA |
| سنة النشر: | 2024 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | acute brain injury, extubation failure, glasgow coma score, mechanical ventilation, ventilator liberation |
| الوصف: | OBJECTIVES:To evaluate the association between the pre-extubation sum of eye and motor components of the Glasgow Coma Score (GCS-EM) and odds of extubation failure in patients with acute brain injury being liberated from mechanical ventilation.DESIGN:Secondary analysis of a prospective, multicenter observational study (ClinicalTrials.gov identifier NCT03400904).SETTING:Sixty-three hospital sites worldwide, with patient recruitment from January 2018 to November 2020.PATIENTS:One thousand one hundred fifty-two critically ill patients with acute brain injury, with a median age of 54 years, of whom 783 (68.0%) were male, 559 (48.5%) had traumatic brain injury, and 905 (78.6%) had a GCS-EM greater than 8 before extubation (scores range from 2 to 10).INTERVENTIONS:None.MEASUREMENTS AND MAIN RESULTS:GCS-EM was computed in intubated patients on the day of extubation. The main outcome was extubation failure, defined as unplanned reintubation within 5 days of extubation. Analyses used multilevel logistic regression with adjustment for patient characteristics and a random intercept for hospital site. In the primary analysis, GCS-EM was not associated with extubation failure (odds ratio, 1.07 per additional point; 95% CI, 0.87-1.31). Findings were consistent in sensitivity analyses that: 1) used different adjustment covariates, 2) included a verbal estimate to derive an overall GCS, 3) accounted for missing data, 4) considered a 2-day time interval to define extubation failure, 5) accounted for competing risks, and 6) used a propensity score-based model. There was no association between GCS-EM and extubation outcome in subgroups defined by brain injury diagnosis or age.CONCLUSIONS:In this large, contemporary, multicenter cohort of patients with acute brain injury, we found no association between the GCS-EM and odds of extubation failure. However, few patients had a pre-extubation GCS-EM less than or equal to 8, and the possibility of a true prognostic association in patients with low scores is not excluded. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/38557684; info:eu-repo/semantics/altIdentifier/wos/WOS:001272373000002; volume:52; issue:8; firstpage:1258; lastpage:1263; numberofpages:6; journal:CRITICAL CARE MEDICINE; https://hdl.handle.net/11573/1723740 |
| DOI: | 10.1097/CCM.0000000000006283 |
| الاتاحة: | https://hdl.handle.net/11573/1723740 https://doi.org/10.1097/CCM.0000000000006283 |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.D6DFDC97 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/CCM.0000000000006283 |
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